Rational Design of Novel Allosteric Dihydrofolate Reductase Inhibitors Showing Antibacterial Effects on Drug-Resistant Escherichia coli Escape Variants.

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Structural and Dynamics Perspectives on the Binding of Substrate and Inhibitors in Mycobacterium tuberculosis DHFR

P2860

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Rational Design of Novel Allosteric Dihydrofolate Reductase Inhibitors Showing Antibacterial Effects on Drug-Resistant Escherichia coli Escape Variants.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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Rational Design of Novel Allos ...... herichia coli Escape Variants.

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Rational Design of Novel Allos ...... herichia coli Escape Variants.

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label

Rational Design of Novel Allos ...... herichia coli Escape Variants.

@en

Rational Design of Novel Allos ...... herichia coli Escape Variants.

@nl

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Rational Design of Novel Allos ...... herichia coli Escape Variants.

@en

Rational Design of Novel Allos ...... herichia coli Escape Variants.

@nl

P1476

Rational Design of Novel Allos ...... herichia coli Escape Variants.

@en

P2093

João V Rodrigues

http://www.w3.org/2001/XMLSchema#string

Sam Tonddast-Navaei

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P2860

Implications of the small number of distinct ligand binding pockets in proteins for drug discovery, evolution and biochemical function

Crystal structures of Sirt3 complexes with 4'-bromo-resveratrol reveal binding sites and inhibition mechanism

Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence

Anticancer antifolates: current status and future directions

Cancer chemopreventive activity of resveratrol, a natural product derived from grapes

Structure-activity and structure-selectivity studies on diaminoquinazolines and other inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase

Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase

A comprehensive survey of small-molecule binding pockets in proteins

PoLi: A Virtual Screening Pipeline Based on Template Pocket and Ligand Similarity.

Ligand binding studies, preliminary structure-activity relationship and detailed mechanistic characterization of 1-phenyl-6,6-dimethyl-1,3,5-triazine-2,4-diamine derivatives as inhibitors of Escherichia coli dihydrofolate reductase.

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1848-1857

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scholarly article

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10.1021/ACSCHEMBIO.7B00175

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P478

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Jeffrey Skolnick

Bharath Srinivasan

Eugene I. Shakhnovich

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2017-05-19T00:00:00Z

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P698

28525268

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allosteric inhibitor

P932

5819740

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Rational Design of Novel Allosteric Dihydrofolate Reductase Inhibitors Showing Antibacterial Effects on Drug-Resistant Escherichia coli Escape Variants.

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P2860

P2860

Rational Design of Novel Allosteric Dihydrofolate Reductase Inhibitors Showing Antibacterial Effects on Drug-Resistant Escherichia coli Escape Variants.

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P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P921

P932