The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
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Induction of a pro-apoptotic ATM-NF-kappaB pathway and its repression by ATR in response to replication stressAfatinib, an Irreversible EGFR Family Inhibitor, Shows Activity Toward Pancreatic Cancer Cells, Alone and in Combination with Radiotherapy, Independent of KRAS Status.Transcription Factors in the Cellular Response to Charged Particle ExposureSignals from within: the DNA-damage-induced NF-kappaB responseEarly termination of ISRCTN45828668, a phase 1/2 prospective, randomized study of sulfasalazine for the treatment of progressing malignant gliomas in adultsATM: a mediator of multiple responses to genotoxic stress.Genetic evidence of a role for ATM in functional interaction between human T-cell leukemia virus type 1 Tax and p53.Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.ATM-NF-kappaB connection as a target for tumor radiosensitizationPhosphorylation of p65(RelA) on Ser(547) by ATM represses NF-κB-dependent transcription of specific genes after genotoxic stress.Ataxia-telangiectasia-mutated (ATM) protein can enhance human immunodeficiency virus type 1 replication by stimulating Rev function.Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)Bystander communication and cell cycle decisions after DNA damageATM: sounding the double-strand break alarm.Nuclear initiated NF-κB signaling: NEMO and ATM take center stage.DNA-damage response network at the crossroads of cell-cycle checkpoints, cellular senescence and apoptosisAblation of XP-V gene causes adipose tissue senescence and metabolic abnormalities.PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation.Quantitative proteomics reveal ATM kinase-dependent exchange in DNA damage response complexes.ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage.MLL1 is essential for the senescence-associated secretory phenotypeType-3 metabotropic glutamate receptors regulate chemoresistance in glioma stem cells, and their levels are inversely related to survival in patients with malignant gliomas.ATM-NFκB axis-driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα.Sam68/KHDRBS1 is critical for colon tumorigenesis by regulating genotoxic stress-induced NF-κB activation.Linking JNK Activity to the DNA Damage Response.The intersection of radiotherapy and immunotherapy: mechanisms and clinical implications.Millepachine, a potential topoisomerase II inhibitor induces apoptosis via activation of NF-κB pathway in ovarian cancer.Effects of an Encapsulated Fruit and Vegetable Juice Concentrate on Obesity-Induced Systemic Inflammation: A Randomised Controlled Trial.IkappaB kinase beta phosphorylates Dok1 serines in response to TNF, IL-1, or gamma radiation.Role of nuclear factor kappaB in liver health and disease.Using NF-κB as a molecular target for theranostics in radiation oncology research.DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out.Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer.Cellular-signaling pathways unveil the carcinogenic potential of chemicals.NF-kappaB activation by camptothecin. A linkage between nuclear DNA damage and cytoplasmic signaling events.Physalin A induces G2/M phase cell cycle arrest in human non-small cell lung cancer cells: involvement of the p38 MAPK/ROS pathway.Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation.Modulation of inflammation and disease tolerance by DNA damage response pathways.2-Deoxy-D-glucose and ferulic acid modulates radiation response signaling in non-small cell lung cancer cells.Elevation of cyclic AMP causes an imbalance between NF-kappaB and p53 in NALM-6 cells treated by doxorubicin.
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P2860
The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
@en
The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
@nl
type
label
The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
@en
The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
@nl
prefLabel
The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
@en
The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
@nl
P2093
P2860
P356
P1433
P1476
The ATM protein is required for sustained activation of NF-kappaB following DNA damage.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1202541
P407
P577
1999-04-01T00:00:00Z