Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid.
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Current trends in oxysterol researchOxidized cholesterol as the driving force behind the development of Alzheimer's diseaseMarked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis.24S,25-Epoxycholesterol in mouse and rat brain.Genetic connections between neurological disorders and cholesterol metabolismEffects of a disrupted blood-brain barrier on cholesterol homeostasis in the brain.Marked accumulation of 27-hydroxycholesterol in the brains of Alzheimer's patients with the Swedish APP 670/671 mutationCholestenoic acids regulate motor neuron survival via liver X receptors.Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator.The oxysterol and cholestenoic acid profile of mouse cerebrospinal fluid.Cholesterol metabolites exported from human brain.Sample prefractionation for mass spectrometry quantification of low-abundance membrane proteins.On the regulatory role of side-chain hydroxylated oxysterols in the brain. Lessons from CYP27A1 transgenic and Cyp27a1(-/-) miceDiscovering oxysterols in plasma: a window on the metabolome.7α-hydroxy-3-oxo-4-cholestenoic acid in cerebrospinal fluid reflects the integrity of the blood-brain barrier.Defective cholesterol metabolism in amyotrophic lateral sclerosis.The effect of APOE genotype on brain levels of oxysterols in young and old human APOE epsilon2, epsilon3 and epsilon4 knock-in mice.The link between altered cholesterol metabolism and Alzheimer's disease.The role of cholesterol metabolism in Alzheimer's disease.Cerebrospinal fluid steroidomics: are bioactive bile acids present in brain?Reduced Plasma Levels of 25-Hydroxycholesterol and Increased Cerebrospinal Fluid Levels of Bile Acid Precursors in Multiple Sclerosis Patients.Evidence for altered cholesterol metabolism in Huntington's disease post mortem brain tissue.Brain Cholesterol Synthesis and Metabolism is Progressively Disturbed in the R6/1 Mouse Model of Huntington's Disease: A Targeted GC-MS/MS Sterol Analysis.On the importance of albumin binding for the flux of 7α-hydroxy-3-oxo-4-cholestenoic acid in the brain.Hereditary spastic paraplegia type 5: natural history, biomarkers and a randomized controlled trial.Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum.Liver disease in infancy caused by oxysterol 7 α-hydroxylase deficiency: successful treatment with chenodeoxycholic acid
P2860
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P2860
Novel route for elimination of brain oxysterols across the blood-brain barrier: conversion into 7alpha-hydroxy-3-oxo-4-cholestenoic acid.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Novel route for elimination of ...... oxy-3-oxo-4-cholestenoic acid.
@en
Novel route for elimination of ...... oxy-3-oxo-4-cholestenoic acid.
@nl
type
label
Novel route for elimination of ...... oxy-3-oxo-4-cholestenoic acid.
@en
Novel route for elimination of ...... oxy-3-oxo-4-cholestenoic acid.
@nl
prefLabel
Novel route for elimination of ...... oxy-3-oxo-4-cholestenoic acid.
@en
Novel route for elimination of ...... oxy-3-oxo-4-cholestenoic acid.
@nl
P2093
P2860
P50
P1476
Novel route for elimination of ...... roxy-3-oxo-4-cholestenoic acid
@en
P2093
John Wahren
Lena Ekström
Magnus Axelsson
Maura Heverin
Ulla Andersson
Wolfgang Sattler
P2860
P304
P356
10.1194/JLR.M600529-JLR200
P577
2007-01-24T00:00:00Z