Dopaminergic deficiency in mice with reduced levels of the dual-specificity tyrosine-phosphorylated and regulated kinase 1A, Dyrk1A(+/-).

Dopaminergic deficiency in mice with reduced levels of the dual-specificity tyrosine-phosphorylated and regulated kinase 1A, Dyrk1A(+/-).

Item
http://www.wikidata.org/entity/Q48351743
Prioritizing the development of mouse models for childhood brain disordersTargeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome.Characterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1.Structural analysis of pathogenic mutations in the DYRK1A gene in patients with developmental disorders.Dyrk1A is dynamically expressed on subsets of motor neurons and in the neuromuscular junction: possible role in Down syndrome.Truncation of the Down syndrome candidate gene DYRK1A in two unrelated patients with microcephaly.MNB/DYRK1A as a multiple regulator of neuronal development.Recent advances in the design, synthesis, and biological evaluation of selective DYRK1A inhibitors: a new avenue for a disease modifying treatment of Alzheimer's?DYRK1A inhibition as potential treatment for Alzheimer's disease.DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease.Overexpression of the DYRK1A Gene (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) Induces Alterations of the Serotoninergic and Dopaminergic Processing in Murine Brain Tissues.Impaired striatal dopamine output of homozygous Wfs1 mutant mice in response to [K+] challenge.
P2860

Dopaminergic deficiency in mice with reduced levels of the dual-specificity tyrosine-phosphorylated and regulated kinase 1A, Dyrk1A(+/-).

Item
http://www.wikidata.org/entity/Q48351743
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Dopaminergic deficiency in mic ...... ulated kinase 1A, Dyrk1A(+/-).
@en
Dopaminergic deficiency in mic ...... ulated kinase 1A, Dyrk1A(+/-).
@nl
type
label
Dopaminergic deficiency in mic ...... ulated kinase 1A, Dyrk1A(+/-).
@en
Dopaminergic deficiency in mic ...... ulated kinase 1A, Dyrk1A(+/-).
@nl
prefLabel
Dopaminergic deficiency in mic ...... ulated kinase 1A, Dyrk1A(+/-).
@en
Dopaminergic deficiency in mic ...... ulated kinase 1A, Dyrk1A(+/-).
@nl
P1433
P1476
P2093
P2860
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Dopaminergic deficiency in mic ...... gulated kinase 1A, Dyrk1A(+/-)
@en
P2093
P2860
P304
P31
P356
10.1111/J.1601-183X.2006.00285.X
P407
P433
P478
P50
P577
P5875
P698
P921