A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody.
about
Insights into antibody catalysis: structure of an oxygenation catalyst at 1.9-angstrom resolutionEvolutionary aspects of immunoglobulin heavy chain variable region (VH) gene subgroupsConservation of sequence in recombination signal sequence spacersAID targeting: old mysteries and new challengesHigh anti-phosphorylcholine antibody levels and mortality associated with pneumoniaCharacterization of human rheumatoid factors with seven antiidiotypes induced by synthetic hypervariable region peptides.Nucleotide sequences and three-dimensional modelling of the VH and VL domains of two human monoclonal antibodies specific for the D antigen of the human Rh-blood-group system.Activation-induced deaminase, AID, is catalytically active as a monomer on single-stranded DNA.Molecular cloning of the primary IgH repertoire: a quantitative analysis of VH gene usage in adult miceSomatic diversification of the S107 (T15) VH11 germ-line gene that encodes the heavy-chain variable region of antibodies to double-stranded DNA in (NZB x NZW)F1 miceAn immunoglobulin mutator that targets G.C base pairs.A coming-of-age story: activation-induced cytidine deaminase turns 10.Eleven distinct VH gene families and additional patterns of sequence variation suggest a high degree of immunoglobulin gene complexity in a lower vertebrate, Xenopus laevis.C-Terminal Domain of Hemocyanin, a Major Antimicrobial Protein from Litopenaeus vannamei: Structural Homology with Immunoglobulins and Molecular DiversityCharacterization of a monoclonal anti-idiotype antibody to human anti-factor VIII antibodiesT cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segmentsOrganization of the murine immunoglobulin VH complex in the inbred strains.Nucleotide sequences of five anti-lysozyme monoclonal antibodiesThe idiotypic network and the internal image: possible regulation of a germ-line network by paucigene encoded Ab2 (anti-idiotypic) antibodies in the GAT system.Interstrain conservation of the murine GAT-specific antibody V kappa repertoire as analyzed at the germline gene levelLooking for relationships between the most repeated dispersed DNA sequences in the mouse: small R elements are found associated consistently with long MIF repeats.VH genes encoding the immune response to beta-(1,6)-galactan: somatic mutation in IgM molecules.Homologous recombination in Escherichia coli: dependence on substrate length and homology.V kappa and J kappa gene segments of A/J Ars-A antibodies: somatic recombination generates the essential arginine at the junction of the variable and joining regionsSignificant structural and functional change of an antigen-binding site by a distant amino acid substitution: proposal of a structural mechanism.Protein evolution on rugged landscapes.Emerging links between hypermutation of antibody genes and DNA polymerases.Adult B-cell repertoire is biased toward two heavy-chain variable-region genes that rearrange frequently in fetal pre-B cellsSomatic diversification of S107 from an antiphosphocholine to an anti-DNA autoantibody is due to a single base change in its heavy chain variable region.Multiple point mutations in a shuttle vector propagated in human cells: evidence for an error-prone DNA polymerase activity.Simple DNA sequences in homologous flanking regions near immunoglobulin VH genes: a role in gene interaction?Somatic evolution of variable region structures during an immune response.IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells.Immunoglobulin diversity: analysis of the germ-line VH gene repertoire of the murine anti-GAT response.Structural relationships among mouse and human immunoglobulin VH genes in the subgroup III.An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development.Highly reduced protection against Streptococcus pneumoniae after deletion of a single heavy chain gene in mouse.Expression of crossreactive idiotypes by human antibodies specific for the capsular polysaccharide of Hemophilus influenzae B.Comparison of junctional diversity in the neonatal and adult immunoglobulin repertoires.A novel class of anti-DNA antibodies identified in BALB/c mice.
P2860
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P2860
A single VH gene segment encodes the immune response to phosphorylcholine: somatic mutation is correlated with the class of the antibody.
description
1981 nî lūn-bûn
@nan
1981年の論文
@ja
1981年学术文章
@wuu
1981年学术文章
@zh
1981年学术文章
@zh-cn
1981年学术文章
@zh-hans
1981年学术文章
@zh-my
1981年学术文章
@zh-sg
1981年學術文章
@yue
1981年學術文章
@zh-hant
name
A single VH gene segment encod ...... ith the class of the antibody.
@en
A single VH gene segment encod ...... ith the class of the antibody.
@nl
type
label
A single VH gene segment encod ...... ith the class of the antibody.
@en
A single VH gene segment encod ...... ith the class of the antibody.
@nl
prefLabel
A single VH gene segment encod ...... ith the class of the antibody.
@en
A single VH gene segment encod ...... ith the class of the antibody.
@nl
P2093
P1433
P1476
A single VH gene segment encod ...... ith the class of the antibody.
@en
P2093
P356
10.1016/0092-8674(81)90231-2
P407
P577
1981-07-01T00:00:00Z