Mutational and expression analysis of the NF1 gene argues against a role as tumor suppressor in sporadic pilocytic astrocytomas. - Wikidata - wikimedia - TriplyDB

Mutational and expression analysis of the NF1 gene argues against a role as tumor suppressor in sporadic pilocytic astrocytomas.

Mutational and expression analysis of the NF1 gene argues against a role as tumor suppressor in sporadic pilocytic astrocytomas.

http://www.wikidata.org/entity/Q48465073

about

The molecular biology of WHO grade I astrocytomas Pathological and molecular advances in pediatric low-grade astrocytoma Neurofibromatosis type 1 - a model for nervous system tumour formation?Solitary plexiform neurofibroma of the stomach: a case report.Pediatric low-grade gliomas and the need for new options for therapy: Why and how?NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer Pathology and molecular genetics of astrocytic gliomas.Targeted Therapy for MAPK Alterations in Pediatric Gliomas.BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas.Current concepts in the molecular genetics of pediatric brain tumors: implications for emerging therapies.Molecular genetics of pediatric central nervous system tumors.Somatic neurofibromatosis type 1 (NF1) inactivation characterizes NF1-associated pilocytic astrocytoma.Pediatric gliomas as neurodevelopmental disorders Using neurofibromatosis-1 to better understand and treat pediatric low-grade glioma Molecular neuropathology of gliomas.MAPK pathway activation and the origins of pediatric low-grade astrocytomas.Review: low-grade gliomas as neurodevelopmental disorders: insights from mouse models of neurofibromatosis-1.Visual acuity in children with low grade gliomas of the visual pathway: implications for patient care and clinical research.The molecular and cell biology of pediatric low-grade gliomas.The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation.Molecular pathology of paediatric central nervous system tumours.Alterations of BRAF and HIPK2 loci predominate in sporadic pilocytic astrocytoma Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma.Disruption of exonic splicing enhancer elements is the principal cause of exon skipping associated with seven nonsense or missense alleles of NF1.Extensive in silico analysis of NF1 splicing defects uncovers determinants for splicing outcome upon 5' splice-site disruption.The diagnostic role and clinical relevance of determination of BRAF status in brain tumors.

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P2860

Mutational and expression analysis of the NF1 gene argues against a role as tumor suppressor in sporadic pilocytic astrocytomas.

http://www.wikidata.org/entity/Q48465073

description

2002 nî lūn-bûn

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2002年の論文

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年学术文章

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2002年學術文章

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2002年學術文章

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name

Mutational and expression anal ...... oradic pilocytic astrocytomas.

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Mutational and expression anal ...... oradic pilocytic astrocytomas.

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type

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Mutational and expression anal ...... oradic pilocytic astrocytomas.

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Mutational and expression anal ...... oradic pilocytic astrocytomas.

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Mutational and expression anal ...... oradic pilocytic astrocytomas.

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Mutational and expression anal ...... oradic pilocytic astrocytomas.

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Journal of Neuropathology & Experimental Neurology

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Mutational and expression anal ...... oradic pilocytic astrocytomas.

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P2093

Birgit Meyer-Puttlitz

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Christa Fonatsch

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Katharina Wimmer

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Markus Eckart

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Torsten Pietsch

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P2860

Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays

Toward a survey of somatic mutation of the NF1 gene in benign neurofibromas of patients with neurofibromatosis type 1.

Haploinsufficiency for the neurofibromatosis 1 (NF1) tumor suppressor results in increased astrocyte proliferation

Modulation of the neurofibromatosis type 1 gene product, neurofibromin, during Schwann cell differentiation

Real time quantitative PCR

The WHO classification of tumors of the nervous system.

Quantitative mRNA analysis of five C-terminal splice variants of the human 5-HT4 receptor in the central nervous system by TaqMan real time RT-PCR.

The diagnostic evaluation and multidisciplinary management of neurofibromatosis 1 and neurofibromatosis 2.

Confirmation of a double-hit model for the NF1 gene in benign neurofibromas.

Urinary bladder transitional cell carcinogenesis is associated with down-regulation of NF1 tumor suppressor gene in vivo and in vitro.

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896-902

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10.1093/JNEN/61.10.896

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10

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61

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