about
Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epitheliumMammalian RanBP1 regulates centrosome cohesion during mitosisLocalized RanGTP accumulation promotes microtubule nucleation at kinetochores in somatic mammalian cellsPart of Ran is associated with AKAP450 at the centrosome: involvement in microtubule-organizing activity.Identification of small molecule inhibitors of the Aurora-A/TPX2 complexNew pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancerAurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forcesDesign and synthesis of 2-heterocyclyl-3-arylthio-1H-indoles as potent tubulin polymerization and cell growth inhibitors with improved metabolic stability.Importin-β negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores.Targeting nuclear transporters in cancer: Diagnostic, prognostic and therapeutic potential.New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer.A role for endogenous reverse transcriptase in tumorigenesis and as a target in differentiating cancer therapy.Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapyToward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitorsThe GTPase Ran: regulation of cell life and potential roles in cell transformation.Mitotic cell death induction by targeting the mitotic spindle with tubulin-inhibitory indole derivative molecules.p53 localization at centrosomes during mitosis and postmitotic checkpoint are ATM-dependent and require serine 15 phosphorylation.Modulation of cell differentiation, proliferation, and tumor growth by dihydrobenzyloxopyrimidine non-nucleoside reverse transcriptase inhibitors.Control of Aurora-A stability through interaction with TPX2.Cytosine methylation transforms an E2F site in the retinoblastoma gene promoter into a binding site for the general repressor methylcytosine-binding protein 2 (MeCP2).RANBP1 localizes a subset of mitotic regulatory factors on spindle microtubules and regulates chromosome segregation in human cells.A role of p73 in mitotic exit.p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle.Different effects of histone H1 on de novo DNA methylation in vitro depend on both the DNA base composition and the DNA methyltransferase.Two E2F sites control growth-regulated and cell cycle-regulated transcription of the Htf9-a/RanBP1 gene through functionally distinct mechanisms.p38 MAPK differentially controls NK activating ligands at transcriptional and post-transcriptional level on multiple myeloma cells.Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays.Importin-β and CRM1 control a RANBP2 spatiotemporal switch essential for mitotic kinetochore function.Ran control of mitosis in human cells: gradients and local signals.Subcellular localization of the five members of the human steroid 5α-reductase family.Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity.p53-independent apoptosis and p53-dependent block of DNA rereplication following mitotic spindle inhibition in human cells.The GTPase RAN regulates multiple steps of the centrosome life cycle.Segmental chromosome aberrations converge on overexpression of mitotic spindle regulatory genes in high-risk neuroblastomaEffect of 5-azacytidine (5-azaC) on the induction of chromatid aberrations (CA) and sister-chromatid exchanges (SCE)Activation of human ribosomal genes by 5-azacytidineClonal inheritance of rRNA gene activity: Cytological evidence in human cellsThe Mitotic Apparatus and Kinetochores in Microcephaly and Neurodevelopmental DiseasesImportin-β/karyopherin-β1 modulates mitotic microtubule function and taxane sensitivity in cancer cells via its nucleoporin-binding region
P50
Q24290276-B1BE9F09-D55B-4445-B01F-5A02274C807FQ28184508-41CDC73E-B8AB-4D4D-9132-9F10D869FC16Q30441480-61EADFFC-4EEF-4628-AEC9-1CD7324FC79AQ30450918-50F1193C-C49A-4335-939B-4B03F81AF8C6Q33762037-1A9B92AE-76EF-4F75-8723-7C325CD4B969Q34133912-E2C9C115-00F6-40AA-94FB-210B40AA6CF2Q35579730-4BD740DA-A0FB-4213-9DFC-AFF7D862C22AQ35682298-85D2B505-3FBA-4515-9BE1-89A45A7814B8Q35770518-B5DFD6B7-6BA7-4E02-B3AD-BBFCAE4AAEBBQ35955008-E7E965EF-6284-4C2C-A9E5-B6DEFED23F44Q36004162-B76EC597-2C50-4F58-90EC-22A9829CB5DAQ36263207-7EF727EE-E741-4350-A7E2-90EFD6E2CB02Q36545796-D1F21833-772A-4985-88A8-E6D74FCFFE93Q36584618-27275709-885D-4341-B385-FE1C0419AA53Q37175250-F81ED035-6463-4089-A733-3FC9629A61C8Q37746123-3010BBA5-2A98-4963-8299-2EB2DDD2C1DBQ39284615-56B13CE2-835A-4FD9-AC93-CF1157B5EACDQ39506980-E7851E20-6ED0-43BF-AD9D-4AD959805FE6Q39621507-CB21D6C2-A971-459C-B772-8F011C3AEFF6Q39728359-C7786F2B-63AE-41D1-B86C-264040463C08Q40067121-333A4750-FF2E-45EA-A9CC-6809D2F32B1DQ40403945-DF97BADC-3D3A-43E1-81FD-BEF5A22F8828Q40803153-C3D7D6B9-BECE-4FF1-B752-0B0CAF7D591AQ42554219-7D2CBFFD-ABE9-4E92-918B-FBDCD63555BAQ42817452-7ABF9563-0441-473D-B3DD-2CC5DD16B261Q45160655-30200EAE-25F5-480F-95B1-4FA7CD0B5341Q48138835-412EA758-A739-452A-9BA6-5707B1CF19EAQ48297889-B3FAFA88-01B5-409C-8E6D-D35BEA13DA94Q48685711-57BB9C41-028E-4F3A-BA21-92E05403092EQ51792401-D03274CA-2AE7-49D2-A2FA-86CE9FCA1A16Q53463432-F0C12AB5-9714-4A35-95F2-A13D2BB927E0Q54086137-0CC1B1C2-AB6C-44F2-B375-34C83771043FQ55059510-C2CF4448-67E7-4DEC-9D92-223045AD76A5Q60819945-AE06A278-E044-4C08-A6EE-E6C08A86A9A9Q60820128-55747B78-8F61-4DC1-8D75-88E1199AA2DEQ60820131-573F2C42-B81F-4A32-9FF1-13865CF32ECCQ60820142-396832CA-B1C1-423E-9835-C34C0D631F4FQ92258721-5A93B3D7-BCEF-44E7-A4AE-45EAEDF71FFEQ93162416-98C321FF-9ACB-407F-B9D3-1602B0CD758A
P50
description
hulumtuese
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Patrizia Lavia
@ast
Patrizia Lavia
@en
Patrizia Lavia
@es
Patrizia Lavia
@nl
Patrizia Lavia
@sl
type
label
Patrizia Lavia
@ast
Patrizia Lavia
@en
Patrizia Lavia
@es
Patrizia Lavia
@nl
Patrizia Lavia
@sl
prefLabel
Patrizia Lavia
@ast
Patrizia Lavia
@en
Patrizia Lavia
@es
Patrizia Lavia
@nl
Patrizia Lavia
@sl
P106
P21
P31
P496
0000-0003-3310-6701
P569
2000-01-01T00:00:00Z