Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.

Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.

Item
http://www.wikidata.org/entity/Q48696474
Novel Acylguanidine Derivatives Targeting Smoothened Induce Antiproliferative and Pro-Apoptotic Effects in Chronic Myeloid Leukemia CellsNew pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancerMRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.Synthetic Small Molecule Inhibitors of Hh Signaling As Anti-Cancer Chemotherapeutics.Small molecule Hedgehog pathway antagonists.Targeting Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2, MK2): Medicinal Chemistry Efforts To Lead Small Molecule Inhibitors to Clinical TrialsHedgehog pathway inhibitors: a patent review (2009--present).Recent advances in the design of Hedgehog pathway inhibitors for the treatment of malignancies.Hedgehog inhibitors: a patent review (2013 - present).Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors.Synthesis of Novel Hybrids Inspired from Bromopyrrole Alkaloids Inhibiting MMP-2 and -12 as Antineoplastic Agents.Strategies to target the Hedgehog signaling pathway for cancer therapy.Novel smoothened antagonists as anti-neoplastic agents for the treatment of osteosarcoma.Targeted inhibition of Hedgehog-GLI signaling by novel acylguanidine derivatives inhibits melanoma cell growth by inducing replication stress and mitotic catastrophe.Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria.Hedgehog signalling pathway inhibitors as cancer suppressing agents
P2860

Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.

Item
http://www.wikidata.org/entity/Q48696474
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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name
Acylthiourea, acylurea, and ac ...... hedgehog inhibiting activity.
@en
Acylthiourea, acylurea, and ac ...... hedgehog inhibiting activity.
@nl
type
label
Acylthiourea, acylurea, and ac ...... hedgehog inhibiting activity.
@en
Acylthiourea, acylurea, and ac ...... hedgehog inhibiting activity.
@nl
prefLabel
Acylthiourea, acylurea, and ac ...... hedgehog inhibiting activity.
@en
Acylthiourea, acylurea, and ac ...... hedgehog inhibiting activity.
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Acylthiourea, acylurea, and ac ...... t hedgehog inhibiting activity
@en
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698