G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
about
Long-Term Potentiation and MemoryRecent progress in understanding subtype specific regulation of NMDA receptors by G Protein Coupled Receptors (GPCRs)Interaction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the Src homology 3 domains of PSD-95 and SAP102HIV-1 Tat through phosphorylation of NMDA receptors potentiates glutamate excitotoxicityAlteration in the voltage dependence of NMDA receptor channels in rat dorsal horn neurones following peripheral inflammationProstaglandin E2 stimulates fibronectin expression through EP1 receptor, phospholipase C, protein kinase Calpha, and c-Src pathway in primary cultured rat osteoblastsGain control of N-methyl-D-aspartate receptor activity by receptor-like protein tyrosine phosphatase alphaScaffolding of Fyn kinase to the NMDA receptor determines brain region sensitivity to ethanol.Co-stimulation of mGluR5 and N-methyl-D-aspartate receptors is required for potentiation of excitatory synaptic transmission in hippocampal neuronsN-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neuronsPKCĪ» is critical in AMPA receptor phosphorylation and synaptic incorporation during LTPThe regulation of N-methyl-D-aspartate receptors by Src kinase.Progesterone-estrogen interactions in synaptic plasticity and neuroprotection.State-dependent Ras signaling and AMPA receptor trafficking.Protein kinase C activation induces tyrosine phosphorylation of the NR2A and NR2B subunits of the NMDA receptor.Expression of splice variants of the NR1 subunit of the N-methyl-D-aspartate receptor in the normal and injured rat spinal cord.H-Ras modulates N-methyl-D-aspartate receptor function via inhibition of Src tyrosine kinase activity.Opinion: Inhibition of Blood-Brain Barrier Repair as a Mechanism in HIV-1 Disease.Mu-opioid receptors transiently activate the Akt-nNOS pathway to produce sustained potentiation of PKC-mediated NMDAR-CaMKII signaling.Caveolae, ion channels and cardiac arrhythmias.Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismCognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction.Signaling cascades regulating NMDA receptor sensitivity to ethanol.Fyn is required for haloperidol-induced catalepsy in mice.Presynaptic serotonin 2A receptors modulate thalamocortical plasticity and associative learningFunctional interaction of mGlu5 and NMDA receptors in aversive learning in rats.The cannabinoid receptor 1 associates with NMDA receptors to produce glutamatergic hypofunction: implications in psychosis and schizophrenia.Neurobiology of lysophosphatidic acid signaling.Targeting N-methyl-D-aspartate receptors for treatment of neuropathic painProtein kinase C promotes N-methyl-D-aspartate (NMDA) receptor trafficking by indirectly triggering calcium/calmodulin-dependent protein kinase II (CaMKII) autophosphorylation.The tyrosine kinase and mitogen-activated protein kinase pathways mediate multiple effects of estrogen in hippocampusAcute ethanol exposure prevents PMA-mediated augmentation of N-methyl-D-aspartate receptor function in primary cultured cerebellar granule cellsNonreceptor tyrosine protein kinase pp60c-src in spatial learning: synapse-specific changes in its gene expression, tyrosine phosphorylation, and protein-protein interactions.Astrocytes increase the activity of synaptic GluN2B NMDA receptorsSRC family kinase inhibitors antagonize the toxicity of multiple serotypes of botulinum neurotoxin in human embryonic stem cell-derived motor neuronsRequirement of phospholipase C and protein kinase C in cholecystokinin-mediated facilitation of NMDA channel function and anxiety-like behavior.5-Hydroxytryptamine 5HT2C receptors form a protein complex with N-methyl-D-aspartate GluN2A subunits and activate phosphorylation of Src protein to modulate motoneuronal depolarization.Regulation of NMDA receptors by phosphorylation.TRPM7 channels in hippocampal neurons detect levels of extracellular divalent cations.SNAP-25 is a target of protein kinase C phosphorylation critical to NMDA receptor trafficking
P2860
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P2860
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
description
1999 nĆ® lÅ«n-bĆ»n
@nan
1999幓ć®č«ę
@ja
1999幓å¦ęÆęē«
@wuu
1999幓å¦ęÆęē«
@zh
1999幓å¦ęÆęē«
@zh-cn
1999幓å¦ęÆęē«
@zh-hans
1999幓å¦ęÆęē«
@zh-my
1999幓å¦ęÆęē«
@zh-sg
1999幓åøč”ęē«
@yue
1999幓åøč”ęē«
@zh-hant
name
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
@en
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
@nl
type
label
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
@en
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
@nl
prefLabel
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
@en
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
@nl
P2093
P2860
P356
P1433
P1476
G-protein-coupled receptors act via protein kinase C and Src to regulate NMDA receptors.
@en
P2093
J F MacDonald
M D Browning
P2860
P2888
P304
P356
10.1038/7243
P407
P577
1999-04-01T00:00:00Z