Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.
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Oxidative Stress Signaling in Alzheimers DiseaseDown-regulation of DENN/MADD, a TNF receptor binding protein, correlates with neuronal cell death in Alzheimer's disease brain and hippocampal neuronsDysfunction of amyloid precursor protein signaling in neurons leads to DNA synthesis and apoptosisc-Jun N-terminal Kinase (JNK) Signaling as a Therapeutic Target for Alzheimer's DiseasePro-Apoptotic Kinase Levels in Cerebrospinal Fluid as Potential Future Biomarkers in Alzheimer's DiseaseNeuropathological alterations in Alzheimer diseaseDown-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's diseaseArgyrophilic grain diseasePalmitoylethanolamide counteracts reactive astrogliosis induced by β-amyloid peptideMolecular profiling reveals diversity of stress signal transduction cascades in highly penetrant Alzheimer's disease human skin fibroblastsStressor-like effects of c-Jun N-terminal kinase (JNK) inhibitionA role for c-Jun N-terminal kinase 1 (JNK1), but not JNK2, in the beta-amyloid-mediated stabilization of protein p53 and induction of the apoptotic cascade in cultured cortical neuronsEffects of NK-4 in a transgenic mouse model of Alzheimer's diseaseXG-102 administered to healthy male volunteers as a single intravenous infusion: a randomized, double-blind, placebo-controlled, dose-escalating study.Direct and indirect roles of cyclin-dependent kinase 5 as an upstream regulator in the c-Jun NH2-terminal kinase cascade: relevance to neurotoxic insults in Alzheimer's disease.The c-jun kinase/stress-activated pathway: regulation, function and role in human disease.Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases.Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease.Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).Altered subcellular distribution of c-Abl in Alzheimer's disease.ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology.Overexpression of matrix metalloproteinase-9 (MMP-9) rescues insulin-mediated impairment in the 5XFAD model of Alzheimer's diseaseNutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease.Molecular mechanisms of neurodegeneration in Alzheimer's disease.Antioxidant therapy in Alzheimer's disease: theory and practice.Causes versus effects: the increasing complexities of Alzheimer's disease pathogenesis.β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathwayThe JNK/c-Jun cascade and Alzheimer's disease.Beta-amyloid oligomers induce phosphorylation of tau and inactivation of insulin receptor substrate via c-Jun N-terminal kinase signaling: suppression by omega-3 fatty acids and curcumin.Genetic modifiers of tauopathy in Drosophila.JNK-interacting protein-1 promotes transcription of A beta protein precursor but not A beta precursor-like proteins, mechanistically different than Fe65MAPKs: new targets for neurodegeneration.Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline.c-Jun N-terminal kinase regulates soluble Aβ oligomers and cognitive impairment in AD mouse model.Activation of the ERK and JNK signaling pathways caused by neuron-specific inhibition of PP2A in transgenic mice.Okadaic-acid-induced inhibition of protein phosphatase 2A produces activation of mitogen-activated protein kinases ERK1/2, MEK1/2, and p70 S6, similar to that in Alzheimer's disease.Co-localization of glycogen synthase kinase-3 with neurofibrillary tangles and granulovacuolar degeneration in transgenic mice.JNK pathway signaling: a novel and smarter therapeutic targets for various biological diseases.Mitochondria and cell bioenergetics: increasingly recognized components and a possible etiologic cause of Alzheimer's disease.Targeting the JNK pathway as a therapeutic protective strategy for nervous system diseases.
P2860
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P2860
Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimer's disease.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Activation and redistribution ...... eurons in Alzheimer's disease.
@en
Activation and redistribution ...... eurons in Alzheimer's disease.
@nl
type
label
Activation and redistribution ...... eurons in Alzheimer's disease.
@en
Activation and redistribution ...... eurons in Alzheimer's disease.
@nl
prefLabel
Activation and redistribution ...... eurons in Alzheimer's disease.
@en
Activation and redistribution ...... eurons in Alzheimer's disease.
@nl
P2093
P1476
Activation and redistribution ...... eurons in Alzheimer's disease.
@en
P2093
P304
P356
10.1046/J.1471-4159.2001.00046.X
P407
P50
P577
2001-01-01T00:00:00Z