A functional connection between the pores of distantly related ion channels as revealed by mutant K+ channels.
about
Functional co-assembly among subunits of cyclic-nucleotide-activated, nonselective cation channels, and across species from nematode to human.Brownian dynamics simulations of interaction between scorpion toxin Lq2 and potassium ion channel.Cyclic nucleotide-gated channels: an expanding new family of ion channelsA family of potassium channel genes related to eag in Drosophila and mammalsTuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sitesThe pharmacology of cyclic nucleotide-gated channels: emerging from the darknessComputational identification of residues that modulate voltage sensitivity of voltage-gated potassium channels.Nanopore-based analysis of biochemical speciesIon concentration-dependent ion conduction mechanism of a voltage-sensitive potassium channelMechanism of potassium-channel selectivity revealed by Na+ and Li+ binding sites within the KcsA poreNovel insights into K+ selectivity from high-resolution structures of an open K+ channel poreCrucial Points within the Pore as Determinants of K+ Channel Conductance and GatingDeterminants of cation transport selectivity: Equilibrium binding and transport kineticsIdentification of a heteromeric interaction that influences the rectification, gating, and pH sensitivity of Kir4.1/Kir5.1 potassium channelsModeling the structure of agitoxin in complex with the Shaker K+ channel: a computational approach based on experimental distance restraints extracted from thermodynamic mutant cyclesCellular processing of cone photoreceptor cyclic GMP-gated ion channels: a role for the S4 structural motifKv2.1 and electrically silent Kv6.1 potassium channel subunits combine and express a novel currentMechanism of Ba(2+) block of a mouse inwardly rectifying K+ channel: differential contribution by two discrete residuesGYGD pore motifs in neighbouring potassium channel subunits interact to determine ion selectivityMechanism underlying slow kinetics of the OFF gating current in Shaker potassium channel.Heteromeric olfactory cyclic nucleotide-gated channels: a subunit that confers increased sensitivity to cAMPInternal Na+ and Mg2+ blockade of DRK1 (Kv2.1) potassium channels expressed in Xenopus oocytes. Inward rectification of a delayed rectifierThe pore-lining region of shaker voltage-gated potassium channels: comparison of beta-barrel and alpha-helix bundle modelsThree-dimensional models of non-NMDA glutamate receptorsStructural correlates of selectivity and inactivation in potassium channels.Structural dynamics of the Streptomyces lividans K+ channel (SKC1): secondary structure characterization from FTIR spectroscopy.TRPV channel-mediated calcium transients in nociceptor neurons are dispensable for avoidance behaviour.Modular Design of the Selectivity Filter Pore Loop in a Novel Family of Prokaryotic 'Inward Rectifier' (NirBac) channelsMolecular cloning of a putative cyclic nucleotide-gated ion channel cDNA from Limulus polyphemus.Primary structure and functional expression of a cGMP-gated potassium channel.Molecular diversity and regulation of renal potassium channels.Molecular determinants of a Ca2+-binding site in the pore of cyclic nucleotide-gated channels: S5/S6 segments control affinity of intrapore glutamates.SLO-2, a K+ channel with an unusual Cl- dependence.Atomic distance estimates from disulfides and high-affinity metal-binding sites in a K+ channel pore.Inositol trisphosphate receptor Ca2+ release channels.Contributions of a negatively charged residue in the hydrophobic domain of the IRK1 inwardly rectifying K+ channel to K(+)-selective permeation.The P-region and S6 of Kv3.1 contribute to the formation of the ion conduction pathwayHydrophobic mutations alter the movement of Mg2+ in the pore of voltage-gated potassium channels.Multiple residues specify external tetraethylammonium blockade in voltage-gated potassium channels.Asymmetric modulation and blockade of the delayed rectifier in squid giant axons by divalent cations.
P2860
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P2860
A functional connection between the pores of distantly related ion channels as revealed by mutant K+ channels.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
A functional connection betwee ...... evealed by mutant K+ channels.
@en
A functional connection betwee ...... evealed by mutant K+ channels.
@nl
type
label
A functional connection betwee ...... evealed by mutant K+ channels.
@en
A functional connection betwee ...... evealed by mutant K+ channels.
@nl
prefLabel
A functional connection betwee ...... evealed by mutant K+ channels.
@en
A functional connection betwee ...... evealed by mutant K+ channels.
@nl
P2093
P356
P1433
P1476
A functional connection betwee ...... evealed by mutant K+ channels.
@en
P2093
Abramson T
Heginbotham L
MacKinnon R
P304
P356
10.1126/SCIENCE.1279807
P407
P577
1992-11-01T00:00:00Z