Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study. - Wikidata - wikimedia - TriplyDB

Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study.

Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study.

http://www.wikidata.org/entity/Q50088470

about

Integrated physiology and systems biology of PPARα Progress and prospects of long noncoding RNAs in lipid homeostasis Visualising associations between paired 'omics' data sets Kernel-PCA data integration with enhanced interpretability.ONION: Functional Approach for Integration of Lipidomics and Transcriptomics Data.Clustering time-series gene expression data using smoothing spline derivatives.Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics.Hepatic steatosis in n-3 fatty acid depleted mice: focus on metabolic alterations related to tissue fatty acid composition Simultaneous analysis of distinct Omics data sets with integration of biological knowledge: Multiple Factor Analysis approach Fenofibrate simultaneously induces hepatic fatty acid oxidation, synthesis, and elongation in mice.Ketone Body Therapy Protects From Lipotoxicity and Acute Liver Failure Upon Pparα Deficiency Dietary flavonoids activate the constitutive androstane receptor (CAR).Transcriptional regulation of human and rat hepatic lipid metabolism by the grapefruit flavonoid naringenin: role of PPARalpha, PPARgamma and LXRalpha.Combination of conjugated linoleic acid with fish oil prevents age-associated bone marrow adiposity in C57Bl/6J mice.Thematic Review Series: Glycerolipids. Multiple roles for lipins/phosphatidate phosphatase enzymes in lipid metabolism.UPLC-MS-based urine metabolomics reveals indole-3-lactic acid and phenyllactic acid as conserved biomarkers for alcohol-induced liver disease in the Ppara-null mouse model Consequences of PPAR(α) Invalidation on Glutathione Synthesis: Interactions with Dietary Fatty Acids.DNA microarray integromics analysis platform.Inferring differentially expressed pathways using kernel maximum mean discrepancy-based test.Robust sparse canonical correlation analysis Sparse kernel canonical correlation analysis for discovery of nonlinear interactions in high-dimensional data Lipidomic profiling reveals protective function of fatty acid oxidation in cocaine-induced hepatotoxicity.Intervention in prediction measure: a new approach to assessing variable importance for random forests.Modulation of PPAR-γ by Nutraceutics as Complementary Treatment for Obesity-Related Disorders and Inflammatory Diseases The lipin protein family: dual roles in lipid biosynthesis and gene expression Biochemistry, physiology, and genetics of GPAT, AGPAT, and lipin enzymes in triglyceride synthesis.Hepatic triacylglycerol hydrolysis regulates peroxisome proliferator-activated receptor alpha activity.Hepatic Fasting-Induced PPARα Activity Does Not Depend on Essential Fatty Acids.Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.PPARs and Mitochondrial Metabolism: From NAFLD to HCC.PPAR-α as a key nutritional and environmental sensor for metabolic adaptation.Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.Role of PPARα in Hepatic Carbohydrate Metabolism.Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study.The nuclear receptor CAR (NR1I3) regulates serum triglyceride levels under conditions of metabolic stress.A Moderate Zinc Deficiency Does Not Impair Gene Expression of PPARα, PPARγ, and Mitochondrial Enoyl-CoA Delta Isomerase in the Liver of Growing Rats Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver.Peroxisome proliferator-activated receptor alpha target genes.Peroxisome proliferator activated receptors and lipoprotein metabolism.Qualitative and Quantitative Evaluation of Dietary Intake in Patients with Non-Alcoholic Steatohepatitis.

P2860

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P2860

Novel aspects of PPARalpha-mediated regulation of lipid and xenobiotic metabolism revealed through a nutrigenomic study.

http://www.wikidata.org/entity/Q50088470

description

2007 nî lūn-bûn

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Novel aspects of PPARalpha-med ...... through a nutrigenomic study.

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Frédéric Lasserre

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Philippe Legrand

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P2860

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

Contrasting effects of fish oil and safflower oil on hepatic peroxisomal and tissue lipid content

Omega-3 fatty acids in inflammation and autoimmune diseases.

Polyunsaturated fatty acids ameliorate hepatic steatosis in obese mice by SREBP-1 suppression.

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