Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease.
about
Autophagy in polyglutamine disease: Imposing order on disorder or contributing to the chaos?Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.Beclin 1 biology and its role in heart disease.Crosstalk Between Macroautophagy and Chaperone-Mediated Autophagy: Implications for the Treatment of Neurological Diseases.Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.Clec16a is Critical for Autolysosome Function and Purkinje Cell SurvivalCaloric restriction blocks neuropathology and motor deficits in Machado-Joseph disease mouse models through SIRT1 pathway.Far-infrared radiation protects viability in a cell model of Spinocerebellar Ataxia by preventing polyQ protein accumulation and improving mitochondrial functionFrom pathways to targets: understanding the mechanisms behind polyglutamine disease.Beclin 1, an Essential Component and Master Regulator of PI3K-III in Health and Disease.The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice.PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation.Neuropeptide Y mitigates neuropathology and motor deficits in mouse models of Machado-Joseph disease.Re-establishing ataxin-2 downregulates translation of mutant ataxin-3 and alleviates Machado-Joseph disease.Let-7 coordinately suppresses components of the amino acid sensing pathway to repress mTORC1 and induce autophagyMitophagy in Parkinson's Disease: Pathogenic and Therapeutic Implications.Transplantation of cerebellar neural stem cells improves motor coordination and neuropathology in Machado-Joseph disease mice.Treatment of Spinocerebellar Ataxia With Mesenchymal Stem Cells: A Phase I/IIa Clinical Study.Human Olfactory Ensheathing Cell Transplantation Improves Motor Function in a Mouse Model of Type 3 Spinocerebellar Ataxia.Deregulation of autophagy in postmortem brains of Machado-Joseph disease patients.Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia.Promoter Variant Alters Expression of the Autophagic BECN1 Gene: Implications for Clinical Manifestations of Machado-Joseph Disease.Repeated Mesenchymal Stromal Cell Treatment Sustainably Alleviates Machado-Joseph Disease
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P2860
Beclin 1 mitigates motor and neuropathological deficits in genetic mouse models of Machado-Joseph disease.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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name
Beclin 1 mitigates motor and n ...... els of Machado-Joseph disease.
@en
Beclin 1 mitigates motor and n ...... els of Machado-Joseph disease.
@nl
type
label
Beclin 1 mitigates motor and n ...... els of Machado-Joseph disease.
@en
Beclin 1 mitigates motor and n ...... els of Machado-Joseph disease.
@nl
prefLabel
Beclin 1 mitigates motor and n ...... els of Machado-Joseph disease.
@en
Beclin 1 mitigates motor and n ...... els of Machado-Joseph disease.
@nl
P2860
P50
P356
P1433
P1476
Beclin 1 mitigates motor and n ...... els of Machado-Joseph disease.
@en
P2093
Isabel Nascimento-Ferreira
P2860
P304
P356
10.1093/BRAIN/AWT144
P407
P50
P577
2013-07-01T00:00:00Z