Assessment of 6'- and 6'''-N-acylation of aminoglycosides as a strategy to overcome bacterial resistance.
about
Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections4′-O-substitutions determine selectivity of aminoglycoside antibioticsComparing aminoglycoside binding sites in bacterial ribosomal RNA and aminoglycoside modifying enzymes.Rapid synthesis, RNA binding, and antibacterial screening of a peptidic-aminosugar (PA) libraryIdentification and characterization of inhibitors of the aminoglycoside resistance acetyltransferase Eis from Mycobacterium tuberculosisSynthesis and Biological Activity of Mono- and Di-N-acylated Aminoglycosides.Biochemical and structural analysis of an Eis family aminoglycoside acetyltransferase from bacillus anthracis.Biochemical and structural analysis of aminoglycoside acetyltransferase Eis from Anabaena variabilisMechanisms of Resistance to Aminoglycoside Antibiotics: Overview and PerspectivesDomain dissection and characterization of the aminoglycoside resistance enzyme ANT(3″)-Ii/AAC(6')-IId from Serratia marcescens.Rise and dissemination of aminoglycoside resistance: the aac(6')-Ib paradigm.Synthesis and evaluation of hetero- and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance.Prospects for circumventing aminoglycoside kinase mediated antibiotic resistance.N6', N6''', and O4' Modifications to Neomycin Affect Ribosomal Selectivity without Compromising Antibacterial Activity.Effects of altering aminoglycoside structures on bacterial resistance enzyme activities.Highly selective acylation of polyamines and aminoglycosides by 5-acyl-5-phenyl-1,5-dihydro-4H-pyrazol-4-ones.Comprehensive review of chemical strategies for the preparation of new aminoglycosides and their biological activities.Evaluation of Aminoglycoside and Carbapenem Resistance in a Collection of Drug-Resistant Pseudomonas aeruginosa Clinical Isolates.Selective modification of the 3''-amino group of kanamycin prevents significant loss of activity in resistant bacterial strains.
P2860
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P2860
Assessment of 6'- and 6'''-N-acylation of aminoglycosides as a strategy to overcome bacterial resistance.
description
2011 nî lūn-bûn
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2011年の論文
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2011年学术文章
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2011年学术文章
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2011年学术文章
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2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
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2011年學術文章
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name
Assessment of 6'- and 6'''-N-a ...... overcome bacterial resistance.
@en
Assessment of 6'- and 6'''-N-a ...... overcome bacterial resistance.
@nl
type
label
Assessment of 6'- and 6'''-N-a ...... overcome bacterial resistance.
@en
Assessment of 6'- and 6'''-N-a ...... overcome bacterial resistance.
@nl
prefLabel
Assessment of 6'- and 6'''-N-a ...... overcome bacterial resistance.
@en
Assessment of 6'- and 6'''-N-a ...... overcome bacterial resistance.
@nl
P2093
P2860
P356
P1476
Assessment of 6'- and 6'''-N-a ...... overcome bacterial resistance.
@en
P2093
Elinor Breiner-Goldstein
Keith D Green
Maria Kramer
Pazit Shaul
Roi Rutenberg
Yifat Berkov-Zrihen
P2860
P304
P356
10.1039/C0OB01133A
P577
2011-03-01T00:00:00Z