Somatic mutation of the MEN1 gene in parathyroid tumours. - Wikidata - wikimedia - TriplyDB

Somatic mutation of the MEN1 gene in parathyroid tumours.

Somatic mutation of the MEN1 gene in parathyroid tumours.

http://www.wikidata.org/entity/Q50623754

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Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis.The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation Menin, a tumor suppressor, associates with nonmuscle myosin II-A heavy chain Menin uncouples Elk-1, JunD and c-Jun phosphorylation from MAP kinase activation Menin, the product of the MEN1 gene, is a nuclear protein HRPT2 mutations are associated with malignancy in sporadic parathyroid tumours Genetic and epigenetic changes in sporadic endocrine tumors: parathyroid tumors Underexpression of Gcm2, a master regulatory gene of parathyroid gland development, in adenomas of primary hyperparathyroidism Identification and characterization of the multiple endocrine neoplasia type 1 (MEN1) gene Germline and somatic mutation of the gene for multiple endocrine neoplasia type 1 (MEN1)MEN1 tumor-suppressor protein localizes to telomeres during meiosis Conditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissues A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors Recurrent ZFX mutations in human sporadic parathyroid adenomas Identification of somatic mutations in parathyroid tumors using whole-exome sequencing Chromosomes, 11Q and cancer: a review.Apoptosis in neuroendocrine tumours.The menin tumor suppressor protein is phosphorylated in response to DNA damage Sporadic endocrine tumours and their relationship to the hereditary endocrine neoplasia syndromes.FBP1 Is an Interacting Partner of Menin.Genetic characterization of large parathyroid adenomas Whole-exome sequencing studies of nonhereditary (sporadic) parathyroid adenomas.Evidence that lymphangiomyomatosis is caused by TSC2 mutations: chromosome 16p13 loss of heterozygosity in angiomyolipomas and lymph nodes from women with lymphangiomyomatosis.Germ-line mutation analysis in patients with multiple endocrine neoplasia type 1 and related disorders Menin immunoreactivity in secretory granules of human pancreatic islet cells Parathyroid tumor development involves deregulation of homeobox genes The DNA methylome of benign and malignant parathyroid tumors.Role of SPECT and SPECT/CT in the Surgical Treatment of Primary Hyperparathyroidism.MEN1 mutations in Hürthle cell (oncocytic) thyroid carcinoma A report of a national mutation testing service for the MEN1 gene: clinical presentations and implications for mutation testing.Hyperparathyroidism with hypercalcaemia in chronic kidney disease: primary or tertiary?Of mice and MEN1: Insulinomas in a conditional mouse knockout.Safety and efficacy of everolimus in adult patients with neuroendocrine tumors.Calcium agonists in hyperparathyroidism.Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms.Patterns of chromosomal imbalances in parathyroid carcinomas The EIF4EBP3 translational repressor is a marker of CDC73 tumor suppressor haploinsufficiency in a parathyroid cancer syndrome.Independent genetic events associated with the development of multiple parathyroid tumors in patients with primary hyperparathyroidism.Rapid mutation screening for HRPT2 and MEN1 mutations associated with familial and sporadic primary hyperparathyroidism.Deletion of 11q23 and cyclin D1 overexpression are frequent aberrations in parathyroid adenomas.

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Somatic mutation of the MEN1 gene in parathyroid tumours.

http://www.wikidata.org/entity/Q50623754

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Somatic mutation of the MEN1 gene in parathyroid tumours.

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Somatic mutation of the MEN1 gene in parathyroid tumours.

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Somatic mutation of the MEN1 gene in parathyroid tumours.

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Somatic mutation of the MEN1 gene in parathyroid tumours.

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Somatic mutation of the MEN1 gene in parathyroid tumours.

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Somatic mutation of the MEN1 gene in parathyroid tumours.

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Somatic mutation of the MEN1 gene in parathyroid tumours.

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Alexander RH

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Burns AL

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Chandrasekharappa SC

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Debelenko LV

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Heppner C

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Kester MB

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P2860

Clonality of parathyroid tumors in familial multiple endocrine neoplasia type 1

Positional cloning of the gene for multiple endocrine neoplasia-type 1

Cyclin D1/PRAD1 expression in parathyroid adenomas: an immunohistochemical study.

A high resolution CEPH crossover mapping panel and integrated map of chromosome 11.

Association of parathyroid tumors in multiple endocrine neoplasia type 1 with loss of alleles on chromosome 11.

Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma.

Loss of heterozygosity studies at the retinoblastoma and breast cancer susceptibility (BRCA2) loci in pituitary, parathyroid, pancreatic and carcinoid tumours.

Primary hyperparathyroidism. Incidence, morbidity, and potential economic impact in a community.

5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.

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