Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.

Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.

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http://www.wikidata.org/entity/Q50702131

Q50702131

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Shotgun lipidomics reveals the temporally dependent, highly diversified cardiolipin profile in the mammalian brain: temporally coordinated postnatal diversification of cardiolipin molecular species with neuronal remodeling Formation of molecular species of mitochondrial cardiolipin. 1. A novel transacylation mechanism to shuttle fatty acids between sn-1 and sn-2 positions of multiple phospholipid species Mammalian patatin domain containing proteins: a family with diverse lipolytic activities involved in multiple biological functions Phospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic intervention Lpx1p is a peroxisomal lipase required for normal peroxisome morphology.Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analyses Calcium-independent phospholipase A2 in rabbit ventricular myocytes Group VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death.Mice deficient in group VIB phospholipase A2 (iPLA2gamma) exhibit relative resistance to obesity and metabolic abnormalities induced by a Western diet.Dysregulation of cardiolipin biosynthesis in pediatric heart failure.Genetic ablation of calcium-independent phospholipase A2gamma leads to alterations in mitochondrial lipid metabolism and function resulting in a deficient mitochondrial bioenergetic phenotype Loss of function variants in human PNPLA8 encoding calcium-independent phospholipase A2 γ recapitulate the mitochondriopathy of the homologous null mouse The metabolic serine hydrolases and their functions in mammalian physiology and disease.Activation of mitochondrial calcium-independent phospholipase A2γ (iPLA2γ) by divalent cations mediating arachidonate release and production of downstream eicosanoids.Calcium-independent phospholipases A2 and their roles in biological processes and diseases.CD36 protein influences myocardial Ca2+ homeostasis and phospholipid metabolism: conduction anomalies in CD36-deficient mice during fasting.Group VIB Phospholipase A(2) promotes proliferation of INS-1 insulinoma cells and attenuates lipid peroxidation and apoptosis induced by inflammatory cytokines and oxidant agents Cardiolipin synthesis for the assembly of bacterial and mitochondrial membranes.Tryptase activates calcium-independent phospholipase A2 and releases PGE2 in airway epithelial cells.Eicosanoid signalling pathways in the heart.Calcium-independent phospholipases in the heart: mediators of cellular signaling, bioenergetics, and ischemia-induced electrophysiologic dysfunction Genetic ablation of calcium-independent phospholipase A2{gamma} leads to alterations in hippocampal cardiolipin content and molecular species distribution, mitochondrial degeneration, autophagy, and cognitive dysfunction.The phospholipase iPLA2γ is a major mediator releasing oxidized aliphatic chains from cardiolipin, integrating mitochondrial bioenergetics and signaling.Cardiac Myocyte-specific Knock-out of Calcium-independent Phospholipase A2γ (iPLA2γ) Decreases Oxidized Fatty Acids during Ischemia/Reperfusion and Reduces Infarct Size.Lipid droplet biogenesis induced by stress involves triacylglycerol synthesis that depends on group VIA phospholipase A2.Rate of acyl migration in lysophosphatidylcholine (LPC) is dependent upon the nature of the acyl group. Greater stability of sn-2 docosahexaenoyl LPC compared to the more saturated LPC species.Lipid Droplets in Cancer: Guardians of Fat in a Stressful World

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P2860

Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.

Item

http://www.wikidata.org/entity/Q50702131

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2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh-hant

name

Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.

@en

Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.

@nl

type

Item

label

Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.

@en

Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.

@nl

prefLabel

Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.

@en

Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.

@nl

P1476

Dramatic accumulation of trigl ...... pendent phospholipase A2gamma.

@en

P2093

Christopher M Jenkins

http://www.w3.org/2001/XMLSchema#string

Dana R Abendschein

http://www.w3.org/2001/XMLSchema#string

David J Mancuso

http://www.w3.org/2001/XMLSchema#string

Harold F Sims

http://www.w3.org/2001/XMLSchema#string

Jeffrey E Saffitz

http://www.w3.org/2001/XMLSchema#string

Jingyue Yang

http://www.w3.org/2001/XMLSchema#string

John J Lehman

http://www.w3.org/2001/XMLSchema#string

Karen Green

http://www.w3.org/2001/XMLSchema#string

Kui Yang

http://www.w3.org/2001/XMLSchema#string

Nandakumar Sambandam

http://www.w3.org/2001/XMLSchema#string

P2860

The genomic organization, complete mRNA sequence, cloning, and expression of a novel human intracellular membrane-associated calcium-independent phospholipase A(2)

A novel intracellular membrane-bound calcium-independent phospholipase A(2)

Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members

Group VIB Ca2+-independent phospholipase A2gamma promotes cellular membrane hydrolysis and prostaglandin production in a manner distinct from other intracellular phospholipases A2

Characterization of the hydroxymethylglutaryl-CoA lyase precursor, a protein targeted to peroxisomes and mitochondria

The neurobiology and evolution of cannabinoid signalling.

Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis

Cleavage of structural proteins during the assembly of the head of bacteriophage T4

Shotgun lipidomics: multidimensional MS analysis of cellular lipidomes

The highly selective production of 2-arachidonoyl lysophosphatidylcholine catalyzed by purified calcium-independent phospholipase A2gamma: identification of a novel enzymatic mediator for the generation of a key branch point intermediate in eicosano

P304

9216-9227

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M607307200

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

282

http://www.w3.org/2001/XMLSchema#string

P577

2007-01-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

17213206

http://www.w3.org/2001/XMLSchema#string

P921

triglyceride homeostasis

hemodynamics

triglyceride

Patatin like phospholipase domain containing 8

Patatin-like phospholipase domain containing 8

Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.

about

P2860

P2860

Dramatic accumulation of triglycerides and precipitation of cardiac hemodynamic dysfunction during brief caloric restriction in transgenic myocardium expressing human calcium-independent phospholipase A2gamma.

description

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type

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P921

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P921