Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.
about
Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fatesThe BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functionsTranscriptional regulation of the NKT cell lineageConvergence of Innate and Adaptive Immunity during Human AgingHomotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage developmentThe Tec family kinase Itk exists as a folded monomer in vivo.Conserved and divergent aspects of human T-cell development and migration in humanized miceTranscriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cellsItk derived signals regulate the expression of Th-POK and controls the development of CD4 T cells.T-Bet independent development of IFNγ secreting natural T helper 1 cell population in the absence of Itk.Phospholipase C{gamma}1 is essential for T cell development, activation, and toleranceDendritic cell-MHC class II and Itk regulate functional development of regulatory innate memory CD4+ T cells in bone marrow transplantation.Cutting edge: innate memory CD8+ T cells are distinct from homeostatic expanded CD8+ T cells and rapidly respond to primary antigenic stimuli.Diacylglycerol Kinase ζ Limits Cytokine-dependent Expansion of CD8+ T Cells with Broad Antitumor Capacity.ITK tunes IL-4-induced development of innate memory CD8+ T cells in a γδ T and invariant NKT cell-independent manner.Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses.T-cell signaling regulated by the Tec family kinase, Itk.Development of innate CD4+ and CD8+ T cells in Itk-deficient mice is regulated by distinct pathwaysDifferential roles of IL-2-inducible T cell kinase-mediated TCR signals in tissue-specific localization and maintenance of skin intraepithelial T cells.Interleukin-4 regulates eomesodermin in CD8+ T cell development and differentiation.Alternative memory in the CD8 T cell lineageLipid signaling in T-cell development and functionInterleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects.Interleukin-2-inducible T cell kinase (Itk) network edge dependence for the maturation of iNKT cell.Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cellsAntigen-inexperienced memory CD8+ T cells: where they come from and why we need them.Immunodeficiency and immune dysregulation associated with proximal defects of T cell receptor signaling.T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cellsLineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice.The tyrosine kinase Itk suppresses CD8+ memory T cell development in response to bacterial infection.Itk signals promote neuroinflammation by regulating CD4+ T-cell activation and trafficking.KLF13 sustains thymic memory-like CD8(+) T cells in BALB/c mice by regulating IL-4-generating invariant natural killer T cells.Jarid2 is induced by TCR signalling and controls iNKT cell maturation.Itk: the rheostat of the T cell response.The signaling symphony: T cell receptor tunes cytokine-mediated T cell differentiationIL-2-inducible T cell kinase tunes T regulatory cell development and is required for suppressive functionPositive selecting cell type determines the phenotype of MHC class Ib-restricted CD8+ T cells.A new look at immune privilege of the eye: dual role for the vision-related molecule retinoic acid.MHC class II-restricted interaction between thymocytes plays an essential role in the production of innate CD8+ T cells.CXCR3 expression defines a novel subset of innate CD8+ T cells that enhance immunity against bacterial infection and cancer upon stimulation with IL-15.
P2860
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P2860
Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Altered development of CD8+ T ...... r the Tec kinases Itk and Rlk.
@en
Altered development of CD8+ T ...... r the Tec kinases Itk and Rlk.
@nl
type
label
Altered development of CD8+ T ...... r the Tec kinases Itk and Rlk.
@en
Altered development of CD8+ T ...... r the Tec kinases Itk and Rlk.
@nl
prefLabel
Altered development of CD8+ T ...... r the Tec kinases Itk and Rlk.
@en
Altered development of CD8+ T ...... r the Tec kinases Itk and Rlk.
@nl
P2093
P1433
P1476
Altered development of CD8+ T ...... r the Tec kinases Itk and Rlk.
@en
P2093
Ana M Venegas
B J Fowlkes
Christine Broussard
Christine Fleischacker
Leslie L Sharp
Madeva Chetana
Pamela L Schwartzberg
Reiko Horai
Stephen M Hedrick
P304
P356
10.1016/J.IMMUNI.2006.05.011
P407
P577
2006-07-01T00:00:00Z