Structural and Chemical Biology of Presenilin Complexes.

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Genetics of β-Amyloid Precursor Protein in Alzheimer's Disease.Antibody Therapeutics Targeting Aβ and Tau.

P2860

Q39047624-EAD3EBDE-9EB6-4BFF-8467-528DE51522B9 Q47591552-57F25B6E-8E45-4DD9-B201-C6948D218150

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Structural and Chemical Biology of Presenilin Complexes.

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http://www.wikidata.org/entity/Q51093204

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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Structural and Chemical Biology of Presenilin Complexes.

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Structural and Chemical Biology of Presenilin Complexes.

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Structural and Chemical Biology of Presenilin Complexes.

@en

Structural and Chemical Biology of Presenilin Complexes.

@nl

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Structural and Chemical Biology of Presenilin Complexes.

@en

Structural and Chemical Biology of Presenilin Complexes.

@nl

P1476

Structural and Chemical Biology of Presenilin Complexes.

@en

P2093

Douglas S Johnson

http://www.w3.org/2001/XMLSchema#string

Martin Pettersson

http://www.w3.org/2001/XMLSchema#string

Peter H St George-Hyslop

http://www.w3.org/2001/XMLSchema#string

Yue-Ming Li

http://www.w3.org/2001/XMLSchema#string

P2860

Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

Consensus analysis of signal peptide peptidase and homologous human aspartic proteases reveals opposite topology of catalytic domains compared with presenilins

Mammalian APH-1 interacts with presenilin and nicastrin and is required for intramembrane proteolysis of amyloid-beta precursor protein and Notch

Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

Nicastrin is critical for stability and trafficking but not association of other presenilin/gamma-secretase components.

Electron microscopic structure of purified, active gamma-secretase reveals an aqueous intramembrane chamber and two pores.

Toward the structure of presenilin/γ-secretase and presenilin homologs

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scholarly article

P356

10.1101/CSHPERSPECT.A024067

http://www.w3.org/2001/XMLSchema#string

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2017-03-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

28320827

http://www.w3.org/2001/XMLSchema#string

P932

5710098

http://www.w3.org/2001/XMLSchema#string

Structural and Chemical Biology of Presenilin Complexes.

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P2860

P2860

Structural and Chemical Biology of Presenilin Complexes.

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P1433

P1476

P2093

P2860

P31

P356

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P31

P356

P433

P478

P577

P698

P932