Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.
about
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi Sarcoma-associated herpesvirus infectionRNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathwayRole of the inflammasome, IL-1β, and IL-18 in bacterial infectionsAtg9a controls dsDNA-driven dynamic translocation of STING and the innate immune responseInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseDifferential splicing of the apoptosis-associated speck like protein containing a caspase recruitment domain (ASC) regulates inflammasomesAspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells.DNA-Encoded Flagellin Activates Toll-Like Receptor 5 (TLR5), Nod-like Receptor Family CARD Domain-Containing Protein 4 (NRLC4), and Acts as an Epidermal, Systemic, and Mucosal-AdjuvantMolecular mechanisms for enhanced DNA vaccine immunogenicity.Aim2 deficiency in mice suppresses the expression of the inhibitory Fcgamma receptor (FcgammaRIIB) through the induction of the IFN-inducible p202, a lupus susceptibility proteinAim2 deficiency stimulates the expression of IFN-inducible Ifi202, a lupus susceptibility murine gene within the Nba2 autoimmune susceptibility locus.Construction of the influenza A virus infection-induced cell-specific inflammatory regulatory network based on mutual information and optimizationPathogenesis of human systemic lupus erythematosus: recent advances.AIM2 Co-immunization with VP1 Is Associated with Increased Memory CD8 T Cells and Mounts Long Lasting Protection against Coxsackievirus B3 Challenge.Stimulator of IFN gene is critical for induction of IFN-beta during Chlamydia muridarum infectionHuman cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein.Signaling and ligand interaction of ILT7: receptor-mediated regulatory mechanisms for plasmacytoid dendritic cellsRecognition of virus infection and innate host responses to viral gene therapy vectors.The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: role in inflammation and autoimmunityIntracellular immunity: finding the enemy within--how cells recognize and respond to intracellular pathogensCaspase-1: the inflammasome and beyond.Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis.Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.Differential roles for the interferon-inducible IFI16 and AIM2 innate immune sensors for cytosolic DNA in cellular senescence of human fibroblasts.Suppression of immune responses by nonimmunogenic oligodeoxynucleotides with high affinity for high-mobility group box proteins (HMGBs)CpG and non-CpG oligodeoxynucleotides directly costimulate mouse and human CD4+ T cells through a TLR9- and MyD88-independent mechanismVirus infection recognition and early innate responses to non-enveloped viral vectors.Inflammasome activation of IL-18 results in endothelial progenitor cell dysfunction in systemic lupus erythematosus.Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activationCyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasomeUse of anti-cancer drugs, mitocans, to enhance the immune responses against tumors.A selective contribution of the RIG-I-like receptor pathway to type I interferon responses activated by cytosolic DNA.Pattern recognition receptors in zebrafish provide functional and evolutionary insight into innate immune signaling pathways.The NLRP3 inflammasome: a sensor for metabolic danger?Dendritic cell function in lupus: Independent contributors or victims of aberrant immune regulation.The interferon-inducible HIN-200 gene family in apoptosis and inflammation: implication for autoimmunity.The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyondA new role for T cells in dampening innate inflammatory responses.Pattern recognition receptors and central nervous system repair.
P2860
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P2860
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.
@en
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.
@nl
type
label
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.
@en
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.
@nl
prefLabel
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.
@en
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.
@nl
P1433
P1476
Innate immunity: cytoplasmic DNA sensing by the AIM2 inflammasome.
@en
P2093
Daniel A Muruve
P304
P356
10.1016/J.CUB.2009.02.011
P407
P577
2009-03-01T00:00:00Z