Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. - Wikidata - wikimedia - TriplyDB

Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis.

Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis.

http://www.wikidata.org/entity/Q34401745

about

Central and overlapping role of Cathepsin B and inflammasome adaptor ASC in antigen presenting function of human dendritic cells Inflammasomes: mechanism of action, role in disease, and therapeutics An Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to Pathology Control of innate and adaptive immunity by the inflammasome Beyond pattern recognition: NOD-like receptors in dendritic cells.The inflammasome: an emerging therapeutic oncotarget for cancer prevention The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity The cytokine release inhibitory drug CRID3 targets ASC oligomerisation in the NLRP3 and AIM2 inflammasomes The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization Inflammasome adaptor protein Apoptosis-associated speck-like protein containing CARD (ASC) is critical for the immune response and survival in west Nile virus encephalitis The inflammasome NLRs in immunity, inflammation, and associated diseases P2X7 blockade attenuates murine lupus nephritis by inhibiting activation of the NLRP3/ASC/caspase 1 pathway.A role for cathepsin Z in neuroinflammation provides mechanistic support for an epigenetic risk factor in multiple sclerosis An interferon-β-resistant and NLRP3 inflammasome-independent subtype of EAE with neuronal damage Deregulated inflammasome signaling in disease.Inflammasome-independent role of the apoptosis-associated speck-like protein containing CARD (ASC) in the adjuvant effect of MF59.Inflammasomes and autoimmunity Inflammasome activation in obesity-related inflammatory diseases and autoimmunity.Role of the Nalp3 inflammasome in acetaminophen-induced sterile inflammation and liver injury.Significant role of IL-1 signaling, but limited role of inflammasome activation, in oviduct pathology during Chlamydia muridarum genital infection The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease NLRs in immune privileged sites Inflammasome is a central player in the induction of obesity and insulin resistance.ASC deficiency suppresses proliferation and prevents medulloblastoma incidence Immune Complexes Indirectly Suppress the Generation of Th17 Responses In Vivo.Toll-like receptor (TLR) and inflammasome actions in the central nervous system Regulation of TH17 cell differentiation by innate immune signals.IL-1 family cytokines trigger sterile inflammatory disease.Interferon-β therapy against EAE is effective only when development of the disease depends on the NLRP3 inflammasome.NLRP3 Inflammasome and MS/EAE.Autophagy and autoimmunity crosstalks Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3.Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself.Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cells The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis.Critical role for the AIM2 inflammasome during acute CNS bacterial infection.T cell-intrinsic ASC critically promotes T(H)17-mediated experimental autoimmune encephalomyelitis Nucleotide-binding oligomerization domain-like receptors and inflammasomes in the pathogenesis of non-microbial inflammation and diseases.Oxidative stress and inflammation interactions in human obesity.

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P2860

Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis.

http://www.wikidata.org/entity/Q34401745

description

2010 nî lūn-bûn

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2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2010 թվականի ապրիլին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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Cutting edge: critical role fo ...... autoimmune encephalomyelitis.

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Cutting edge: critical role fo ...... autoimmune encephalomyelitis.

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Cutting edge: critical role fo ...... autoimmune encephalomyelitis.

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Cutting edge: critical role fo ...... autoimmune encephalomyelitis.

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Cutting edge: critical role fo ...... autoimmune encephalomyelitis.

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Cutting edge: critical role fo ...... autoimmune encephalomyelitis.

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JIMMUNOL.1000217

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Journal of Immunology

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Cutting edge: critical role fo ...... autoimmune encephalomyelitis.

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Maureen A McGargill

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Patrick J Shaw

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Samir Burns

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P2860

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

Autoimmune T cell responses in the central nervous system

Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis

NALP3: a key player in caspase-1 activation.

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4610-4614

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scholarly article

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10.4049/JIMMUNOL.1000217

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9

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184

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Thirumala-Devi Kanneganti

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2010-04-05T00:00:00Z

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43023249

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20368281

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experimental autoimmune encephalomyelitis

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3001131

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