ODDD-linked Cx43 mutants reduce endogenous Cx43 expression and function in osteoblasts and inhibit late stage differentiation.
about
Connexins: a myriad of functions extending beyond assembly of gap junction channelsOsteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodelingStructure and functional studies of N-terminal Cx43 mutants linked to oculodentodigital dysplasia.A dominant loss-of-function GJA1 (Cx43) mutant impairs parturition in the mouseCharacterization of hTERT-immortalized osteoblast cell lines generated from wild-type and connexin43-null mouse calvaria.Syndromic and non-syndromic disease-linked Cx43 mutations.Up-regulation of BMP2/4 signaling increases both osteoblast-specific marker expression and bone marrow adipogenesis in Gja1Jrt/+ stromal cell cultures.The transcriptional activity of osterix requires the recruitment of Sp1 to the osteocalcin proximal promoter.Neuropeptide Y, substance P, and human bone morphogenetic protein 2 stimulate human osteoblast osteogenic activity by enhancing gap junction intercellular communication.CONNEXIN 43 AND BONE: NOT JUST A GAP JUNCTION PROTEIN.Connexinopathies: a structural and functional glimpseBeyond gap junctions: Connexin43 and bone cell signalingConnexins in the skeletonThe regulation of runt-related transcription factor 2 by fibroblast growth factor-2 and connexin43 requires the inositol polyphosphate/protein kinase Cδ cascadeEffect of magnesium ion on human osteoblast activity.Oogenesis defects in a mutant mouse model of oculodentodigital dysplasia.The C-terminal domain of connexin43 modulates cartilage structure via chondrocyte phenotypic changes.Overview of skin diseases linked to connexin gene mutations.Molecular mechanisms of osteoblast/osteocyte regulation by connexin43.The "connexin" between bone cells and skeletal functions.Regulation of gap junction function and Connexin 43 expression by cytochrome P450 oxidoreductase (CYPOR).Connexin43 Mutant Patient-Derived Induced Pluripotent Stem Cells Exhibit Altered Differentiation Potential.The G60S connexin 43 mutation activates the osteoblast lineage and results in a resorption-stimulating bone matrix and abrogation of old-age-related bone loss.
P2860
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P2860
ODDD-linked Cx43 mutants reduce endogenous Cx43 expression and function in osteoblasts and inhibit late stage differentiation.
description
2008 nî lūn-bûn
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
@zh-cn
2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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name
ODDD-linked Cx43 mutants reduc ...... it late stage differentiation.
@en
ODDD-linked Cx43 mutants reduc ...... it late stage differentiation.
@nl
type
label
ODDD-linked Cx43 mutants reduc ...... it late stage differentiation.
@en
ODDD-linked Cx43 mutants reduc ...... it late stage differentiation.
@nl
prefLabel
ODDD-linked Cx43 mutants reduc ...... it late stage differentiation.
@en
ODDD-linked Cx43 mutants reduc ...... it late stage differentiation.
@nl
P2093
P2860
P356
P1476
ODDD-linked Cx43 mutants reduc ...... it late stage differentiation.
@en
P2093
Elizabeth McLachlan
Gerald M Kidder
Isabelle Plante
Suzanne M Bernier
P2860
P304
P356
10.1359/JBMR.080217
P50
P577
2008-06-01T00:00:00Z