A mouse model for Down syndrome exhibits learning and behaviour deficits. - Wikidata - wikimedia - TriplyDB

A mouse model for Down syndrome exhibits learning and behaviour deficits.

A mouse model for Down syndrome exhibits learning and behaviour deficits.

http://www.wikidata.org/entity/Q52013436

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Primary and secondary transcriptional effects in the developing human Down syndrome brain and heart DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase Prospects for Improving Brain Function in Individuals with Down Syndrome Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region Trisomy-21 gene dosage over-expression of miRNAs results in the haploinsufficiency of specific target proteins Down's syndrome suppression of tumour growth and the role of the calcineurin inhibitor DSCR1 Human microRNA-155 on chromosome 21 differentially interacts with its polymorphic target in the AGTR1 3' untranslated region: a mechanism for functional single-nucleotide polymorphisms related to phenotypes The functional nature of synaptic circuitry is altered in area CA3 of the hippocampus in a mouse model of Down's syndrome Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders Dissecting Alzheimer disease in Down syndrome using mouse models Behavioral and Genetic Evidence for GIRK Channels in the CNS: Role in Physiology, Pathophysiology, and Drug Addiction Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities Modelling human disease with pluripotent stem cells Dendritic spine dysgenesis in autism related disorders Wnt signaling in neuropsychiatric disorders: ties with adult hippocampal neurogenesis and behavior Down Syndrome Cognitive Phenotypes Modeled in Mice Trisomic for All HSA 21 Homologues Hippocampal circuit dysfunction in the Tc1 mouse model of Down syndrome.Principal Component Analysis of the Effects of Environmental Enrichment and (-)-epigallocatechin-3-gallate on Age-Associated Learning Deficits in a Mouse Model of Down Syndrome Synaptic Vesicle Recycling Is Unaffected in the Ts65Dn Mouse Model of Down Syndrome Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration Synaptopathies: synaptic dysfunction in neurological disorders - A review from students to students Modeling a model: Mouse genetics, 22q11.2 Deletion Syndrome, and disorders of cortical circuit development Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome Functional screening of 2 Mb of human chromosome 21q22.2 in transgenic mice implicates minibrain in learning defects associated with Down syndrome Olig1 and Olig2 triplication causes developmental brain defects in Down syndrome Chromosome 21 and down syndrome: from genomics to pathophysiology Animal models of intellectual disability: towards a translational approach Characterization of PTZ-induced seizure susceptibility in a down syndrome mouse model that overexpresses CSTB Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment Pharmacotherapy with fluoxetine restores functional connectivity from the dentate gyrus to field CA3 in the Ts65Dn mouse model of down syndrome Dosage of the Abcg1-U2af1 region modifies locomotor and cognitive deficits observed in the Tc1 mouse model of Down syndrome Unraveling the genetic architecture of copy number variants associated with schizophrenia and other neuropsychiatric disorders.Pharmacological approaches to improving cognitive function in Down syndrome: current status and considerations.Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer.Auditory function in the Tc1 mouse model of down syndrome suggests a limited region of human chromosome 21 involved in otitis media.The use of mouse models to understand and improve cognitive deficits in Down syndrome.Behavioral validation of the Ts65Dn mouse model for Down syndrome of a genetic background free of the retinal degeneration mutation Pde6b(rd1).Live imaging of neuronal connections by magnetic resonance: Robust transport in the hippocampal-septal memory circuit in a mouse model of Down syndrome.Advanced microscopic imaging methods to investigate cortical development and the etiology of mental retardation.A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions.

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P2860

A mouse model for Down syndrome exhibits learning and behaviour deficits.

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1995 nî lūn-bûn

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A mouse model for Down syndrome exhibits learning and behaviour deficits.

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A mouse model for Down syndrome exhibits learning and behaviour deficits.

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A mouse model for Down syndrome exhibits learning and behaviour deficits.

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A mouse model for Down syndrome exhibits learning and behaviour deficits.

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A mouse model for Down syndrome exhibits learning and behaviour deficits.

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A mouse model for Down syndrome exhibits learning and behaviour deficits.

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Bronson RT

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Davisson MT

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Irving NG

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10.1038/NG1095-177

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