In utero rearrangements in the trithorax-related oncogene in infant leukaemias.
about
Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6.Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemiaDietary flavonoids and the MLL gene: A pathway to infant leukemia?t(11;22)(q23;q11.2) In acute myeloid leukemia of infant twins fuses MLL with hCDCrel, a cell division cycle gene in the genomic region of deletion in DiGeorge and velocardiofacial syndromesDietary bioflavonoids induce cleavage in the MLL gene and may contribute to infant leukemiaMammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathwaysCritical windows of exposure to household pesticides and risk of childhood leukemiaRevisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemiaAcute myeloid leukaemia: a paradigm for the clonal evolution of cancer?How animal models of leukaemias have already benefited patientsChildhood acute lymphoblastic leukemia: Integrating genomics into therapyGerminal and Somatic Trisomy 21 Mosaicism: How Common is it, What are the Implications for Individual Carriers and How Does it Come About?Biomarkers of leukemia risk: benzene as a modelGPHN, a novel partner gene fused to MLL in a leukemia with t(11;14)(q23;q24).Pre-leukemic evolution of hematopoietic stem cells: the importance of early mutations in leukemogenesisDiscordance of MLL-rearranged (MLL-R) infant acute lymphoblastic leukemia in monozygotic twins with spontaneous clearance of preleukemic clone in unaffected twin.Array CGH in human leukemia: from somatics to genetics.Leukaemia and Sellafield: is there a heritable link?The prenatal origins of cancerMll rearrangements in haematological malignancies: lessons from clinical and biological studies.Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots.Childhood leukaemia.Cytogenetics and molecular genetics of childhood leukemia.Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoiresExposure to infections and risk of leukemia in young children.Critical windows of exposure for children's health: cancer in human epidemiological studies and neoplasms in experimental animal modelsMaternal and offspring genetic variants of AKR1C3 and the risk of childhood leukemia.Chromosome translocations and covert leukemic clones are generated during normal fetal developmentMLL-SEPTIN6 fusion recurs in novel translocation of chromosomes 3, X, and 11 in infant acute myelomonocytic leukaemia and in t(X;11) in infant acute myeloid leukaemia, and MLL genomic breakpoint in complex MLL-SEPTIN6 rearrangement is a DNA topoisomThe landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemiasCured meat, vegetables, and bean-curd foods in relation to childhood acute leukemia risk: a population based case-control study.Genetic and molecular analysis of region 88E9;88F2 in Drosophila melanogaster, including the ear gene related to human factors involved in lineage-specific leukemias.Genetic profile of acute myeloid leukemia.Gender-specific frequency of background somatic mutations at the hypoxanthine phosphoribosyltransferase locus in cord blood T lymphocytes from preterm newborns.Prenatal exposure of mice to the human liver carcinogen aflatoxin B1 reveals a critical window of susceptibility to genetic change.Methylenetetrahydrofolate reductase (MTHFR) polymorphisms and risk of molecularly defined subtypes of childhood acute leukemiaARID5B polymorphism confers an increased risk to acquire specific MLL rearrangements in early childhood leukemia.Recent advances in the treatment of infant acute myeloid leukemia.mll ortholog containing functional domains of human MLL is expressed throughout the zebrafish lifespan and in haematopoietic tissues
P2860
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P2860
In utero rearrangements in the trithorax-related oncogene in infant leukaemias.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
In utero rearrangements in the trithorax-related oncogene in infant leukaemias.
@en
In utero rearrangements in the trithorax-related oncogene in infant leukaemias.
@nl
type
label
In utero rearrangements in the trithorax-related oncogene in infant leukaemias.
@en
In utero rearrangements in the trithorax-related oncogene in infant leukaemias.
@nl
prefLabel
In utero rearrangements in the trithorax-related oncogene in infant leukaemias.
@en
In utero rearrangements in the trithorax-related oncogene in infant leukaemias.
@nl
P2093
P356
P1433
P1476
In utero rearrangements in the trithorax-related oncogene in infant leukaemias.
@en
P2093
Cabrera ME
P2888
P304
P356
10.1038/363358A0
P407
P577
1993-05-01T00:00:00Z
P6179
1011201106