Pyruvate kinase M2 interacts with nuclear sterol regulatory element-binding protein 1a and thereby activates lipogenesis and cell proliferation in hepatocellular carcinoma.

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New links between lipid accumulation and cancer progression.Emerging role of lipid metabolism alterations in Cancer stem cells.High PKM2 expression is independently correlated with decreased overall survival in hepatocellular carcinoma

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Pyruvate kinase M2 interacts with nuclear sterol regulatory element-binding protein 1a and thereby activates lipogenesis and cell proliferation in hepatocellular carcinoma.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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Pyruvate kinase M2 interacts w ...... n in hepatocellular carcinoma.

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Pyruvate kinase M2 interacts w ...... n in hepatocellular carcinoma.

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Pyruvate kinase M2 interacts w ...... n in hepatocellular carcinoma.

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Pyruvate kinase M2 interacts w ...... n in hepatocellular carcinoma.

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Pyruvate kinase M2 interacts w ...... n in hepatocellular carcinoma.

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Pyruvate kinase M2 interacts w ...... n in hepatocellular carcinoma.

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Pyruvate kinase M2 interacts w ...... n in hepatocellular carcinoma.

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Fajun Yang

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Gang Huang

http://www.w3.org/2001/XMLSchema#string

Hao Yang

http://www.w3.org/2001/XMLSchema#string

Jiajin Li

http://www.w3.org/2001/XMLSchema#string

Jianjun Liu

http://www.w3.org/2001/XMLSchema#string

Li Zhao

http://www.w3.org/2001/XMLSchema#string

Xiaoping Zhao

http://www.w3.org/2001/XMLSchema#string

Xuejie Min

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Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway

Pyruvate kinase M2 is a PHD3-stimulated coactivator for hypoxia-inducible factor 1

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

Akt stimulates hepatic SREBP1c and lipogenesis through parallel mTORC1-dependent and independent pathways

Regulation of lipogenesis by cyclin-dependent kinase 8-mediated control of SREBP-1

Transcriptional activities of nuclear SREBP-1a, -1c, and -2 to different target promoters of lipogenic and cholesterogenic genes

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy.

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

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scholarly article

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10.1074/JBC.RA117.000100

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293

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Pyruvate kinase M2 interacts with nuclear sterol regulatory element-binding protein 1a and thereby activates lipogenesis and cell proliferation in hepatocellular carcinoma.

about

P2860

P2860

Pyruvate kinase M2 interacts with nuclear sterol regulatory element-binding protein 1a and thereby activates lipogenesis and cell proliferation in hepatocellular carcinoma.

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