PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells. - Wikidata - wikimedia - TriplyDB

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

http://www.wikidata.org/entity/Q34654908

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Myosins as fundamental components during tumorigenesis: diverse and indispensable Pyruvate kinase: Function, regulation and role in cancer Pyruvate kinase M2 at a glance Phosphorylation of the regulatory light chain of myosin in striated muscle: methodological perspectives Pyruvate kinase type M2 promotes tumour cell exosome release via phosphorylating synaptosome-associated protein 23 Interaction with Pyruvate Kinase M2 Destabilizes Tristetraprolin by Proteasome Degradation and Regulates Cell Proliferation in Breast Cancer.Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation.Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis.PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis.Eph-mediated tyrosine phosphorylation of citron kinase controls abscission Additional energy scale in SmB6 at low-temperature Transcription factors, transcriptional coregulators, and epigenetic modulation in the control of pulmonary vascular cell phenotype: therapeutic implications for pulmonary hypertension (2015 Grover Conference series).Mitochondrial PKM2 regulates oxidative stress-induced apoptosis by stabilizing Bcl2.Myosin di-phosphorylation and peripheral actin bundle formation as initial events during endothelial barrier disruption.Pyruvate kinase M2 interacts with mammalian sterile 20-like kinase 1 and inhibits tamoxifen-induced apoptosis in human breast cancer cells.Oxygen availability and metabolic adaptations.PKM2, cancer metabolism, and the road ahead.Epigenetic silencing of miR-338 facilitates glioblastoma progression by de-repressing the pyruvate kinase M2-β-catenin axis.Phosphorylation of myosin regulatory light chain controls myosin head conformation in cardiac muscle.Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis A Novel Role for Pyruvate Kinase M2 as a Corepressor for P53 during the DNA Damage Response in Human Tumor Cells.Glucose Catabolism in Liver Tumors Induced by c-MYC Can Be Sustained by Various PKM1/PKM2 Ratios and Pyruvate Kinase Activities.PKM2 in carcinogenesis and oncotherapy.Pyruvate kinase M2 phosphorylates H2AX and promotes genomic instability in human tumor cells.LincRNA-p21 suppresses development of human prostate cancer through inhibition of PKM2.Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy.Inhibiting aerobic glycolysis suppresses renal interstitial fibroblast activation and renal fibrosis.Metabolic Kinases Moonlighting as Protein Kinases.Pyruvate kinase M2 fuels multiple aspects of cancer cells: from cellular metabolism, transcriptional regulation to extracellular signaling.Pyruvate kinase M2 interacts with nuclear sterol regulatory element-binding protein 1a and thereby activates lipogenesis and cell proliferation in hepatocellular carcinoma.Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia.EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation.Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways.

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P2860

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

http://www.wikidata.org/entity/Q34654908

description

2014 nî lūn-bûn

@nan

2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

@zh-hk

2014年論文

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2014年論文

@zh-tw

2014年论文

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name

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

@ast

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

@en

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

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type

label

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

@ast

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

@en

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

@nl

prefLabel

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

@ast

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

@en

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells.

@nl

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P1433

Nature Communications

P1476

PKM2 phosphorylates MLC2 and regulates cytokinesis of tumour cells

@en

P2093

David X Liu

http://www.w3.org/2001/XMLSchema#string

Erfei Bi

http://www.w3.org/2001/XMLSchema#string

Qin Zhou

http://www.w3.org/2001/XMLSchema#string

Sadhan Majumder

http://www.w3.org/2001/XMLSchema#string

Suyun Huang

http://www.w3.org/2001/XMLSchema#string

Ting Wang

http://www.w3.org/2001/XMLSchema#string

Xinjian Li

http://www.w3.org/2001/XMLSchema#string

Yanhua Zheng

http://www.w3.org/2001/XMLSchema#string

Yugang Wang

http://www.w3.org/2001/XMLSchema#string

Yuhui Jiang

http://www.w3.org/2001/XMLSchema#string

P2860

Rocks: multifunctional kinases in cell behaviour

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Pyruvate kinase M2 is a phosphotyrosine-binding protein

Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

Abnormal cardiac structure and function in mice expressing nonphosphorylatable cardiac regulatory myosin light chain 2

Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells

Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process

Pyruvate kinase type M2 and its role in tumor growth and spreading

Chemical genetic screen for AMPKα2 substrates uncovers a network of proteins involved in mitosis

Cancer cell metabolism: Warburg and beyond

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5566

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scholarly article

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10.1038/NCOMMS6566

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P478

5

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2014-11-21T00:00:00Z

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1036005919

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25412762

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phosphorylation

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4259466

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