Presenilins and the intramembrane proteolysis of proteins: facts and fiction.

Presenilins and the intramembrane proteolysis of proteins: facts and fiction.

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http://www.wikidata.org/entity/Q53244411
CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide productionPresenilin and nicastrin regulate each other and determine amyloid beta-peptide production via complex formationBACE1 and presenilin: two unusual aspartyl proteases involved in Alzheimer's diseasePhosphorylated KDR can be located in the nucleus of neoplastic cells.A gamma-secretase inhibitor blocks Notch signaling in vivo and causes a severe neurogenic phenotype in zebrafishHPRT deficiency coordinately dysregulates canonical Wnt and presenilin-1 signaling: a neuro-developmental regulatory role for a housekeeping gene?The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms.The beta-amyloid precursor protein (APP) and Alzheimer's disease: does the tail wag the dog?Dependency of γ-secretase complex activity on the structural integrity of the bilayer.Positive and negative regulation of APP amyloidogenesis by sumoylation.The role of proteases in regulating Eph/ephrin signaling.The expression and cellular localization of phosphorylated VEGFR2 in lymphoma and non-neoplastic lymphadenopathy: an immunohistochemical study.Presenilins mutated at Asp-257 or Asp-385 restore Pen-2 expression and Nicastrin glycosylation but remain catalytically inactive in the absence of wild type Presenilin.
P2860

Presenilins and the intramembrane proteolysis of proteins: facts and fiction.

Item
http://www.wikidata.org/entity/Q53244411
description
2001 nî lūn-bûn
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
@zh-my
2001年学术文章
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2001年學術文章
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2001年學術文章
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name
Presenilins and the intramembrane proteolysis of proteins: facts and fiction.
@en
Presenilins and the intramembrane proteolysis of proteins: facts and fiction.
@nl
type
label
Presenilins and the intramembrane proteolysis of proteins: facts and fiction.
@en
Presenilins and the intramembrane proteolysis of proteins: facts and fiction.
@nl
prefLabel
Presenilins and the intramembrane proteolysis of proteins: facts and fiction.
@en
Presenilins and the intramembrane proteolysis of proteins: facts and fiction.
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P698
P921
P356
P1433
P1476
Presenilins and the intramembrane proteolysis of proteins: facts and fiction.
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P577
P698
P921