p53-dependent translational control of senescence and transformation via 4E-BPs. - Wikidata - wikimedia - TriplyDB

p53-dependent translational control of senescence and transformation via 4E-BPs.

p53-dependent translational control of senescence and transformation via 4E-BPs.

http://www.wikidata.org/entity/Q53305156

about

Amino acid management in cancer The expanding role of mTOR in cancer cell growth and proliferation Growth-arrest-specific protein 2 inhibits cell division in Xenopus embryos mTOR signaling in tumorigenesis Autism-related deficits via dysregulated eIF4E-dependent translational control.Identification of differential translation in genome wide studies New frontiers in translational control of the cancer genome Cellular senescence and protein degradation: breaking down cancer Targeting mTOR dependency in pancreatic cancer The role of TGFBI in mesothelioma and breast cancer: association with tumor suppression.The evolution of the TOR pathway and its role in cancer.mTORC1 signaling under hypoxic conditions is controlled by ATM-dependent phosphorylation of HIF-1α.Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1-dependent.Requirement for the eIF4E binding proteins for the synergistic down-regulation of protein synthesis by hypertonic conditions and mTOR inhibition eIF4E threshold levels differ in governing normal and neoplastic expansion of mammary stem and luminal progenitor cells.Proteomics analysis of normal and senescent NG108-15 cells: GRP78 plays a negative role in cisplatin-induced senescence in the NG108-15 cell line.Translational regulation in nutrigenomics.Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1.The AMPK stress response pathway mediates anoikis resistance through inhibition of mTOR and suppression of protein synthesis.IRES-mediated translation of foot-and-mouth disease virus (FMDV) in cultured cells derived from FMDV-susceptible and -insusceptible animals.Distinct perturbation of the translatome by the antidiabetic drug metformin Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence MicroRNAs 125a and 125b inhibit ovarian cancer cells through post-transcriptional inactivation of EIF4EBP1 Superior efficacy of co-treatment with dual PI3K/mTOR inhibitor NVP-BEZ235 and pan-histone deacetylase inhibitor against human pancreatic cancer.The Role of Dynamics and Allostery in the Inhibition of the eIF4E/eIF4G Translation Initiation Factor Complex Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth.ZRF1 is a novel S6 kinase substrate that drives the senescence programme.Targeting translation dependence in cancer Cap and cap-binding proteins in the control of gene expression.Translational control of cell fate: from integration of environmental signals to breaching anticancer defense.Targeting Mnks for cancer therapy.Anti-oncogenic potential of the eIF4E-binding proteins.Regulation of mRNA translation by signaling pathways Many roads from mTOR to eIF4F.Ribosomal proteins as novel players in tumorigenesis.Differential Regulation of the Melanoma Proteome by eIF4A1 and eIF4E.PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer.Eukaryotic initiation factor 4E-binding protein 1 (4E-BP1): a master regulator of mRNA translation involved in tumorigenesis.Rapamycin restores p14, p15 and p57 expression and inhibits the mTOR/p70S6K pathway in acute lymphoblastic leukemia cells.

P2860

Q26798087-E73A3BC2-1030-40FC-AF30-D44D6B8C62B3 Q27027797-8BAD5751-7FD9-4475-B6F1-BC644A9059AA Q27320579-62067094-9DE6-4659-A238-CB1BB0631946 Q28252695-228428CA-EB5B-447B-87D4-492EBD22769D Q28592812-5D644E8C-5EC3-44BE-93EB-33DDD8920108 Q30497672-46D00D42-CACE-4356-8375-FAB5329BEBF3 Q33853235-9A1E653D-15C1-42CC-91D2-5332305D8F8E Q33953067-021BCDBC-8A71-4665-BA24-F4CA2F16A510 Q34092334-E768E592-7E19-4DCB-A998-34C602312A8C Q34303247-D9BB5355-1726-450B-93D5-5EFB6EDA943C Q34318188-1E8CA761-71C7-4199-B122-A60498EA0DEF Q34418791-C2C0F211-02F1-4888-B2CF-B80AA91B49D8 Q34471836-1AF51229-7139-439D-BC8D-1DB3E6A38CE7 Q34936880-B9C5F91F-D8D5-4301-A98A-2323AFE252BD Q35096727-96345A4F-F6FB-4EBF-8111-6F75BE191CDF Q35118638-8A52FE6E-BF9C-472D-ABFC-5D1D7DC084A8 Q35579583-8BCDC5C6-1F62-4685-A92F-C3ACF618DCDC Q35640152-DA45E03F-2D08-40F0-89F4-B67A55E12147 Q35694634-8B579686-92D8-4906-A290-BB6E19B45724 Q35754698-B136EDF5-D3DC-45FF-847A-695761A1162A Q35976938-5E66A838-8CD0-4670-967E-43B094F1F875 Q36061621-25B99D12-3D13-425C-B47D-5DF9D8920774 Q36126248-F0C48C0D-1DBD-47E5-A4D3-A307D0F61C5C Q36962391-1AC06203-33FF-43A2-AC01-D093758E7086 Q37030911-05F875D3-D065-495D-B8A1-B91EB54E7214 Q37255081-C71EDC09-61B7-481C-8774-C6B03075EE6C Q37500185-3D6FE5A8-C843-44F2-9ADB-FBE46D8F63AF Q37700183-B59D3745-A9F7-48E0-9356-37B11D720EFB Q37850227-53EDD949-3B7B-45A4-914A-4FB35155B089 Q37940415-AD91298A-2021-49AE-AED8-3835D858739E Q37987280-B7ACF82A-A22E-4B0A-958E-C082D05DC3F3 Q37990881-30627A5A-AADF-4531-BF10-0F9C834D5EEA Q38003091-E90B5BCD-EC19-4266-9AE6-527E8C2242B3 Q38034202-42541E35-E5FD-499F-AA86-9EB2386843AF Q38122222-68FEBF6D-6601-45F4-841F-CA6356B7650F Q38174514-E9A6440C-7FBB-43CB-A01D-15F9CBCA1964 Q38290067-4470B533-168C-4615-BEBE-9D4C31D1B39E Q38698803-229C3522-8D3B-4963-92DB-038364C0DF7A Q38717560-EB64B3EA-80E9-4B2D-B269-D3E6891F5EBE Q38835910-0CDB0227-08A4-4A76-B0B0-7E008ED07D30

P2860

p53-dependent translational control of senescence and transformation via 4E-BPs.

http://www.wikidata.org/entity/Q53305156

description

2009 nî lūn-bûn

@nan

2009年の論文

@ja

2009年学术文章

@wuu

2009年学术文章

@zh

2009年学术文章

@zh-cn

2009年学术文章

@zh-hans

2009年学术文章

@zh-my

2009年学术文章

@zh-sg

2009年學術文章

@yue

2009年學術文章

@zh-hant

name

p53-dependent translational control of senescence and transformation via 4E-BPs.

@en

p53-dependent translational control of senescence and transformation via 4E-BPs.

@nl

type

label

p53-dependent translational control of senescence and transformation via 4E-BPs.

@en

p53-dependent translational control of senescence and transformation via 4E-BPs.

@nl

prefLabel

p53-dependent translational control of senescence and transformation via 4E-BPs.

@en

p53-dependent translational control of senescence and transformation via 4E-BPs.

@nl

P1433

Q53305156-8B14AD6E-F0A0-419E-B836-AE1D75B7DA73

P1476

Q53305156-21105767-DC0F-4A52-BD28-E45D5AA0FD54

P2093

Q53305156-0A15323F-129F-4A23-BDCB-B77CE66DC89D

Q53305156-14C138A9-4411-4821-989D-6A6FFD48F595

Q53305156-1F360FA5-2584-4014-9198-5762A4040196

Q53305156-532B58B7-3BF4-4089-A591-7BEACCD3D3CD

Q53305156-5764B7FD-4104-47E7-BA2F-C2A22017AE07

Q53305156-73B0D908-9D13-41C5-A903-7F10ECFFBC5A

Q53305156-91FDA4AB-2F36-4570-B5CC-13A070002F35

Q53305156-991EE201-C192-49FF-8317-584932BA208F

Q53305156-A0640587-3E12-432D-98C5-674112588C77

Q53305156-A4CAB70C-5F50-4CDD-9CEE-A0B5E4B8486D

P304

Q53305156-C58CC14C-15A3-4081-B6E0-03880D42487A

P31

Q53305156-9CC503B9-A794-4925-9116-292EB477D2D4

P356

Q53305156-144FCB3F-D712-486D-AD08-F91E850F1963

P433

Q53305156-9C38FD26-98A8-4F90-9811-A9383BB4116C

P478

Q53305156-3ABEE39A-2013-4432-8C02-3817C7854936

P50

Q53305156-1E8A562E-D58D-457A-9DBE-6EE69C97F317

Q53305156-6F71D4BB-2685-4D1C-AC36-10B822F3C7E0

Q53305156-7CB23E8D-EE46-48A1-B022-E1740C051479

Q53305156-A267B33C-B2C2-42A3-9EAA-249C28B39EE5

Q53305156-C3652620-6EC4-424C-8E53-DD99E2791486

Q53305156-C7D38590-9DAD-42B8-B199-5C71AC677ADE

Q53305156-F04677F7-5812-4C89-8FA9-4434F5F6FE15

P577

Q53305156-97BA63A6-7C93-4D22-8422-794CF7D6852A

P5875

Q53305156-75716AEE-6626-4B3A-B192-DB2ACE12FD56

P698

Q53305156-71EDEFAE-2530-4415-B8F1-D2642DA894E6

P356

J.CCR.2009.09.025

P1433

P1476

p53-dependent translational control of senescence and transformation via 4E-BPs.

@en

P2093

Armen Parsyan

http://www.w3.org/2001/XMLSchema#string

David Shahbazian

http://www.w3.org/2001/XMLSchema#string

Emmanuel Petroulakis

http://www.w3.org/2001/XMLSchema#string

Liwei Rong

http://www.w3.org/2001/XMLSchema#string

Marilene Paquet

http://www.w3.org/2001/XMLSchema#string

Mauro Costa-Mattioli

http://www.w3.org/2001/XMLSchema#string

Michael Bidinosti

http://www.w3.org/2001/XMLSchema#string

Olivier LeBacquer

http://www.w3.org/2001/XMLSchema#string

Ryan J O Dowling

http://www.w3.org/2001/XMLSchema#string

Tommy Alain

http://www.w3.org/2001/XMLSchema#string

P304

439-446

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.CCR.2009.09.025

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

16

http://www.w3.org/2001/XMLSchema#string

P50

Mark Livingstone

Ivan Topisirovic

Jose G. Teodoro

Nahum Sonenberg

P577

2009-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

38057157

http://www.w3.org/2001/XMLSchema#string

P698

19878875

http://www.w3.org/2001/XMLSchema#string