Collagen-homology domain 1 deletion mutant of Shc suppresses transformation mediated by neu through a MAPK-independent pathway.

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Biological activity of the thyroid TRK-T3 oncogene requires signalling through Shc siRNA-based targeting of cyclin E overexpression inhibits breast cancer cell growth and suppresses tumor development in breast cancer mouse model.

P2860

Q24648398-6D4139C1-27B9-4056-9FC3-BC763515FFB0 Q33705021-226DD923-191F-4EC2-830D-158A10AB4D60

P2860

Collagen-homology domain 1 deletion mutant of Shc suppresses transformation mediated by neu through a MAPK-independent pathway.

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http://www.wikidata.org/entity/Q53423117

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1999 nî lūn-bûn

@nan

1999年の論文

@ja

1999年学术文章

@wuu

1999年学术文章

@zh

1999年学术文章

@zh-cn

1999年学术文章

@zh-hans

1999年学术文章

@zh-my

1999年学术文章

@zh-sg

1999年學術文章

@yue

1999年學術文章

@zh-hant

name

Collagen-homology domain 1 del ...... gh a MAPK-independent pathway.

@en

Collagen-homology domain 1 del ...... gh a MAPK-independent pathway.

@nl

type

Item

label

Collagen-homology domain 1 del ...... gh a MAPK-independent pathway.

@en

Collagen-homology domain 1 del ...... gh a MAPK-independent pathway.

@nl

prefLabel

Collagen-homology domain 1 del ...... gh a MAPK-independent pathway.

@en

Collagen-homology domain 1 del ...... gh a MAPK-independent pathway.

@nl

P1476

Collagen-homology domain 1 del ...... gh a MAPK-independent pathway.

@en

P2093

Hung MC

http://www.w3.org/2001/XMLSchema#string

Li K

http://www.w3.org/2001/XMLSchema#string

Shao R

http://www.w3.org/2001/XMLSchema#string

P2860

The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling

Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene

The PTB domain: a new protein module implicated in signal transduction

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1

Dominant-negative mutants of Grb2 induced reversal of the transformed phenotypes caused by the point mutation-activated rat HER-2/Neu

P2888

sj.onc.1202605

P304

2617-2626

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1202605

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

1999-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

12944518

http://www.w3.org/2001/XMLSchema#string

P698

10353605

http://www.w3.org/2001/XMLSchema#string

Collagen-homology domain 1 deletion mutant of Shc suppresses transformation mediated by neu through a MAPK-independent pathway.

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P2860

P2860

Collagen-homology domain 1 deletion mutant of Shc suppresses transformation mediated by neu through a MAPK-independent pathway.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P577

P5875

P698