The ankyrin-binding domain of CD44s is involved in regulating hyaluronic acid-mediated functions and prostate tumor cell transformation.
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Hyaluronan-mediated CD44 interaction with p300 and SIRT1 regulates beta-catenin signaling and NFkappaB-specific transcription activity leading to MDR1 and Bcl-xL gene expression and chemoresistance in breast tumor cellsCD44 cell adhesion moleculesHyaluronan-CD44 interaction promotes c-Src-mediated twist signaling, microRNA-10b expression, and RhoA/RhoC up-regulation, leading to Rho-kinase-associated cytoskeleton activation and breast tumor cell invasionAnkyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migrationCD44 interaction with c-Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migrationSodium channel beta subunits mediate homophilic cell adhesion and recruit ankyrin to points of cell-cell contactHyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growthCytoskeletal regulation of CD44 membrane organization and interactions with E-selectin.Spontaneous metastasis of prostate cancer is promoted by excess hyaluronan synthesis and processing.Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells.Nonreceptor tyrosine kinases in prostate cancer.CD44 engagement promotes matrix-derived survival through the CD44-SRC-integrin axis in lipid raftsHyaluronan and hyaluronidase in genitourinary tumors.Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression.Role of miR-647 in human gastric cancer suppressionSrc signaling pathways in prostate cancer.Interaction between CD44 and the repeat domain of ankyrin promotes hyaluronic acid-mediated ovarian tumor cell migration.Heregulin-mediated ErbB2-ERK signaling activates hyaluronan synthases leading to CD44-dependent ovarian tumor cell growth and migration.Hyaluronan-CD44 interaction with neural Wiskott-Aldrich syndrome protein (N-WASP) promotes actin polymerization and ErbB2 activation leading to beta-catenin nuclear translocation, transcriptional up-regulation, and cell migration in ovarian tumor ceCortactin underpins CD44-promoted invasion and adhesion of breast cancer cells to bone marrow endothelial cells.Src-/- fibroblasts are defective in their ability to disassemble focal adhesions in response to phorbol ester/hyaluronan treatment.CD44 stimulation by fragmented hyaluronic acid induces upregulation of urokinase-type plasminogen activator and its receptor and subsequently facilitates invasion of human chondrosarcoma cells.Hyaluronan promotes signaling interaction between CD44 and the transforming growth factor beta receptor I in metastatic breast tumor cells.Synthesis and shedding of hyaluronan from plasma membranes of human fibroblasts and metastatic and non-metastatic melanoma cells.A novel CD44 v3 isoform is involved in head and neck squamous cell carcinoma progression.CD44v10 interaction with Rho-kinase (ROK) activates inositol 1,4,5-triphosphate (IP3) receptor-mediated Ca2+ signaling during hyaluronan (HA)-induced endothelial cell migration.Regulation of drug resistance and metastasis of gastric cancer cells via the microRNA647-ANK2 axis.PanCD44 Immunohistochemical Evaluation in Prostatectomies from Patients with Adenocarcinoma.
P2860
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P2860
The ankyrin-binding domain of CD44s is involved in regulating hyaluronic acid-mediated functions and prostate tumor cell transformation.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
The ankyrin-binding domain of ...... ate tumor cell transformation.
@en
The ankyrin-binding domain of ...... ate tumor cell transformation.
@nl
type
label
The ankyrin-binding domain of ...... ate tumor cell transformation.
@en
The ankyrin-binding domain of ...... ate tumor cell transformation.
@nl
prefLabel
The ankyrin-binding domain of ...... ate tumor cell transformation.
@en
The ankyrin-binding domain of ...... ate tumor cell transformation.
@nl
P2860
P1433
P1476
The ankyrin-binding domain of ...... ate tumor cell transformation.
@en
P2093
P2860
P304
P356
10.1002/(SICI)1097-0169(1998)39:3<209::AID-CM4>3.0.CO;2-#
P577
1998-01-01T00:00:00Z