Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes.
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Human cord blood stem cell-modulated regulatory T lymphocytes reverse the autoimmune-caused type 1 diabetes in nonobese diabetic (NOD) miceDendritic cell subsets in type 1 diabetes: friend or foe?Inhibition of Autoimmune Diabetes in NOD Mice by miRNA TherapyTregs and kidney: From diabetic nephropathy to renal transplantationH2 control of natural T regulatory cell frequency in the lymph node correlates with susceptibility to day 3 thymectomy-induced autoimmune diseaseDefects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjectsPre-existing autoimmunity determines type 1 diabetes outcome after Flt3-ligand treatment.Effector and naturally occurring regulatory T cells display no abnormalities in activation induced cell death in NOD miceInflammatory tendencies and overproduction of IL-17 in the colon of young NOD mice are counteracted with diet change.How punctual ablation of regulatory T cells unleashes an autoimmune lesion within the pancreatic isletsInterleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy.Alteration of the thymic T cell repertoire by rotavirus infection is associated with delayed type 1 diabetes development in non-obese diabetic mice.Natural regulatory T cells in autoimmunity.IL-21 signaling is critical for the development of type I diabetes in the NOD mouse.GABA exerts protective and regenerative effects on islet beta cells and reverses diabetesDominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion.Ganglioside GM1 deficiency in effector T cells from NOD mice induces resistance to regulatory T-cell suppressionEvaluation of immunosuppressive function of regulatory T cells using a novel in vitro cytotoxicity assayTh1-Like ICOS+ Foxp3+ Treg Cells Preferentially Express CXCR3 and Home to β-Islets during Pre-Diabetes in BDC2.5 NOD MiceHelminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-β.Broad induction of immunoregulatory mechanisms after a short course of anti-IL-7Rα antibodies in NOD mice.Induced Foxp3(+) regulatory T cells: a potential new weapon to treat autoimmune and inflammatory diseases?The influence of CD4+ CD25+ Foxp3+ regulatory T cells on the immune response to rotavirus infection.The Critical Role of TGF-beta1 in the Development of Induced Foxp3+ Regulatory T CellsTargeting regulatory T cells in the treatment of type 1 diabetes mellitus.The defect in T-cell regulation in NOD mice is an effect on the T-cell effectorsRegulatory T cells vs Th17: differentiation of Th17 versus Treg, are the mutually exclusive?Commonality in the genetic control of Type 1 diabetes in humans and NOD mice: variants of genes in the IL-2 pathway are associated with autoimmune diabetes in both species.Genetic deficiency of Itgb2 or ItgaL prevents autoimmune diabetes through distinctly different mechanisms in NOD/LtJ mice.Immunoregulatory mechanisms triggered by viral infections protect from type 1 diabetes in miceβ-cell-specific IL-2 therapy increases islet Foxp3+Treg and suppresses type 1 diabetes in NOD mice.Culture promotes transfer of thyroid epithelial cell hyperplasia and proliferation by reducing regulatory T cell numbers.Thymic development of autoreactive T cells in NOD mice is regulated in an age-dependent mannerSingular role for T-BET+CXCR3+ regulatory T cells in protection from autoimmune diabetes.Regulatory T cells and inhibitory cytokines in autoimmunity.Treg cells in pancreatic lymph nodes: the possible role in diabetogenesis and β cell regeneration in a T1D model.Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease.Autoimmunity and the pathogenesis of type 1 diabetes.Functional plasticity in human FOXP3(+) regulatory T cells: implications for cell-based immunotherapy.Immune Regulation in T1D and T2D: Prospective Role of Foxp3+ Treg Cells in Disease Pathogenesis and Treatment.
P2860
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P2860
Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Functional waning of naturally ...... onset of autoimmune diabetes.
@en
Functional waning of naturally ...... onset of autoimmune diabetes.
@nl
type
label
Functional waning of naturally ...... onset of autoimmune diabetes.
@en
Functional waning of naturally ...... onset of autoimmune diabetes.
@nl
prefLabel
Functional waning of naturally ...... onset of autoimmune diabetes.
@en
Functional waning of naturally ...... onset of autoimmune diabetes.
@nl
P2093
P356
P1433
P1476
Functional waning of naturally ...... onset of autoimmune diabetes.
@en
P2093
Ciriaco A Piccirillo
Eva d'Hennezel
Evridiki Sgouroudis
Michael Tritt
P304
P356
10.2337/DB06-1700
P407
P577
2007-10-10T00:00:00Z