The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children.
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PIAS1 interacts with FLASH and enhances its co-activation of c-MybA functional SUMO-interacting motif in the transactivation domain of c-Myb regulates its myeloid transforming abilityNew tricks from an old oncogene: gene fusion and copy number alterations of MYB in human cancerGene expression profiling identifies a subset of adult T-cell acute lymphoblastic leukemia with myeloid-like gene features and over-expression of miR-223Fusion oncogenes in salivary gland tumors: molecular and clinical consequencesTranscriptional network control of normal and leukaemic haematopoiesisTargeted sequencing identifies associations between IL7R-JAK mutations and epigenetic modulators in T-cell acute lymphoblastic leukemiaInsertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1Reduced c-Myb activity compromises HSCs and leads to a myeloproliferation with a novel stem cell basisPHF6 mutations in T-cell acute lymphoblastic leukemiac-Myb and its target Bmi1 are required for p190BCR/ABL leukemogenesis in mouse and human cellsErythroblastic sarcoma presenting as bilateral ovarian masses in an infant with pure erythroid leukemia.c-Myb promotes the survival of CD4+CD8+ double-positive thymocytes through upregulation of Bcl-xLRequirement of c-Myb for p210(BCR/ABL)-dependent transformation of hematopoietic progenitors and leukemogenesisCombined interphase fluorescence in situ hybridization elucidates the genetic heterogeneity of T-cell acute lymphoblastic leukemia in adults.c-Myb binds MLL through menin in human leukemia cells and is an important driver of MLL-associated leukemogenesis.The chicken miR-150 targets the avian orthologue of the functional zebrafish MYB 3'UTR target site.Global genomic characterization of acute lymphoblastic leukemiamicroRNA profiling in Epstein-Barr virus-associated B-cell lymphoma.Dramatic repositioning of c-Myb to different promoters during the cell cycle observed by combining cell sorting with chromatin immunoprecipitation.Pediatric low-grade gliomas: how modern biology reshapes the clinical field.Detection of fetomaternal genotype associations in early-onset disorders: evaluation of different methods and their application to childhood leukemiaSingle molecule analysis of c-myb alternative splicing reveals novel classifiers for precursor B-ALL.Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia.Deletion of the protein tyrosine phosphatase gene PTPN2 in T-cell acute lymphoblastic leukemia.C/EBPα and MYB regulate FLT3 expression in AMLPediatric T-cell lymphoblastic leukemia evolves into relapse by clonal selection, acquisition of mutations and promoter hypomethylation.MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas.GFI1B, EVI5, MYB--additional genes that cooperate with the human BCL6 gene to promote the development of lymphomasIntegrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by MybSite- and allele-specific polycomb dysregulation in T-cell leukaemiaClonal selection in xenografted human T cell acute lymphoblastic leukemia recapitulates gain of malignancy at relapseAn integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance.MicroRNA-193b-3p acts as a tumor suppressor by targeting the MYB oncogene in T-cell acute lymphoblastic leukemiaAnimal-specific C-terminal domain links myeloblastosis oncoprotein (Myb) to an ancient repressor complex.Novel chromosomal rearrangements and break points at the t(6;9) in salivary adenoid cystic carcinoma: association with MYB-NFIB chimeric fusion, MYB expression, and clinical outcome.Mutations of PHF6 are associated with mutations of NOTCH1, JAK1 and rearrangement of SET-NUP214 in T-cell acute lymphoblastic leukemia.The histone acetyltransferase TIP60 interacts with c-Myb and inactivates its transcriptional activity in human leukemia.c-Myb regulates matrix metalloproteinases 1/9, and cathepsin D: implications for matrix-dependent breast cancer cell invasion and metastasis.Danio rerio: Small Fish Making a Big Splash in Leukemia
P2860
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P2860
The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
The C-MYB locus is involved in ...... ubtype in very young children.
@en
The C-MYB locus is involved in ...... ubtype in very young children.
@nl
type
label
The C-MYB locus is involved in ...... ubtype in very young children.
@en
The C-MYB locus is involved in ...... ubtype in very young children.
@nl
prefLabel
The C-MYB locus is involved in ...... ubtype in very young children.
@en
The C-MYB locus is involved in ...... ubtype in very young children.
@nl
P2093
P1433
P1476
The C-MYB locus is involved in ...... ubtype in very young children.
@en
P2093
Alain Aurias
Alan M Gewirtz
André Baruchel
Anna Kalota
Antoine Crinquette
Anton W Langerak
Bertrand Montpellier
Bertrand Nadel
Emmanuelle Clappier
Francois Sigaux
P304
P356
10.1182/BLOOD-2006-12-064683
P407
P577
2007-04-23T00:00:00Z