The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity.
about
Emerging therapeutic roles for NAD(+) metabolism in mitochondrial and age-related disordersPotential Modulation of Sirtuins by Oxidative StressSirtuins as regulators of metabolism and healthspanStructural Basis for Enzymatic Evolution from a Dedicated ADP-ribosyl Cyclase to a Multifunctional NAD HydrolaseUndercover: gene control by metabolites and metabolic enzymesEvolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathologyDeleted in breast cancer-1 regulates SIRT1 activity and contributes to high-fat diet-induced liver steatosis in mice.Recent progress in metabolic signaling pathways regulating aging and life spanThe secret life of NAD+: an old metabolite controlling new metabolic signaling pathways.Sirtuins: guardians of mammalian healthspan.It takes two to tango: NAD+ and sirtuins in aging/longevity controlNAD+ and sirtuins in aging and disease.Characterization of NAD uptake in mammalian cells.The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling.PARP-1 inhibition increases mitochondrial metabolism through SIRT1 activationIncreasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism.Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation.Exploring the genetic signature of body size in Yucatan miniature pig.Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility.Epigenome-wide study identifies novel methylation loci associated with body mass index and waist circumference.NAD(+) Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the NucleusRole of deleted in breast cancer 1 (DBC1) protein in SIRT1 deacetylase activation induced by protein kinase A and AMP-activated protein kinase.Altered hepatic lipid metabolism in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptorExploring the therapeutic space around NAD+.SIRT1 and energy metabolism.Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome.The NAD(+) precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet-induced obesity.Mitochondrial sirtuins and metabolic homeostasisMetabolic consequences of pregnancy-associated plasma protein-A deficiency in mice: exploring possible relationship to the longevity phenotype.CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism.Sirtuin activation as a therapeutic approach against inborn errors of metabolism.The importance of NAD in multiple sclerosisCD38 Deficiency Protects the Heart from Ischemia/Reperfusion Injury through Activating SIRT1/FOXOs-Mediated Antioxidative Stress Pathway.The importance of NAMPT/NAD/SIRT1 in the systemic regulation of metabolism and ageing.CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions.NAD⁺ metabolism: a therapeutic target for age-related metabolic disease.Pharmacological approaches to restore mitochondrial function.Accurate measurement of nicotinamide adenine dinucleotide (NAD⁺) with high-performance liquid chromatography.Targeting of NAD metabolism in pancreatic cancer cells: potential novel therapy for pancreatic tumors.Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health.
P2860
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P2860
The enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
The enzyme CD38 (a NAD glycohy ...... pment of diet-induced obesity.
@en
The enzyme CD38 (a NAD glycohy ...... pment of diet-induced obesity.
@nl
type
label
The enzyme CD38 (a NAD glycohy ...... pment of diet-induced obesity.
@en
The enzyme CD38 (a NAD glycohy ...... pment of diet-induced obesity.
@nl
prefLabel
The enzyme CD38 (a NAD glycohy ...... pment of diet-induced obesity.
@en
The enzyme CD38 (a NAD glycohy ...... pment of diet-induced obesity.
@nl
P2093
P356
P1433
P1476
The enzyme CD38 (a NAD glycohy ...... pment of diet-induced obesity.
@en
P2093
Colleen M Novak
Eduardo Nunes Chini
James A Levine
Maria Thereza P Barbosa
Pinar Aksoy
Sandra M Soares
P304
P356
10.1096/FJ.07-8290COM
P407
P577
2007-06-21T00:00:00Z