Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis.
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ABC transporters as multidrug resistance mechanisms and the development of chemosensitizers for their reversalRepacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycleABC transporter research: going strong 40 years onProviding a molecular mechanism for P-glycoprotein; why would I bother?Molecular action of sulphonylureas on KATP channels: a real partnership between drugs and nucleotidesThe interaction of ApoA-I and ABCA1 triggers signal transduction pathways to mediate efflux of cellular lipidsAntibody C219 recognizes an alpha-helical epitope on P-glycoproteinA single chain Fv fragment of P-glycoprotein-specific monoclonal antibody C219. Design, expression, and crystal structure at 2.4 A resolutionMolecular properties of bacterial multidrug transportersRole of glycine-534 and glycine-1179 of human multidrug resistance protein (MDR1) in drug-mediated control of ATP hydrolysisThe strong in vivo anti-tumor effect of the UIC2 monoclonal antibody is the combined result of Pgp inhibition and antibody dependent cell-mediated cytotoxicityThree-dimensional structure of transporter associated with antigen processing (TAP) obtained by single Particle image analysisFitting the elementary rate constants of the P-gp transporter network in the hMDR1-MDCK confluent cell monolayer using a particle swarm algorithmThe homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanismXenobiotic efflux in bacteria and fungi: a genomics updateGenetic separation of FK506 susceptibility and drug transport in the yeast Pdr5 ATP-binding cassette multidrug resistance transporter.Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites.Merck Frosst Award Lecture 1998. Molecular dissection of the human multidrug resistance P-glycoprotein.Xenobiotic, bile acid, and cholesterol transporters: function and regulation.P-glycoprotein-mediated resistance to chemotherapy in cancer cells: using recombinant cytosolic domains to establish structure-function relationships.Cystic fibrosis transmembrane conductance regulator. Structure and function of an epithelial chloride channel.The structure of the multidrug resistance protein 1 (MRP1/ABCC1). crystallization and single-particle analysis.Clinical significance of ABCB1 genotyping in oncology.Drug delivery across the blood-brain barrier: why is it difficult? how to measure and improve it?Analysis of the PilQ secretin from Neisseria meningitidis by transmission electron microscopy reveals a dodecameric quaternary structure.A family of drug transporters: the multidrug resistance-associated proteins.Symmetry and structure in P-glycoprotein and ABC transporters what goes around comes around.Multidrug resistance ABC transporters.Regulation of bacterial drug export systemsThe multi-structural feature of the multidrug resistance gene product P-glycoprotein: implications for its mechanism of action (hypothesis).Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters.ABCB1 variation and treatment response in AIDS patients: initial results of the Henan cohortInfluence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages.Recent advances in the discovery of flavonoids and analogs with high-affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance.Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein)The role of Multidrug Resistance-1 (MDR1) variants in response to atorvastatin among Jordanians.Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs.AcrB multidrug efflux pump of Escherichia coli: composite substrate-binding cavity of exceptional flexibility generates its extremely wide substrate specificity.Structure and function of efflux pumps that confer resistance to drugsRegulation of ABCA1 functions by signaling pathways
P2860
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P2860
Structure of the multidrug resistance P-glycoprotein to 2.5 nm resolution determined by electron microscopy and image analysis.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年学术文章
@wuu
1997年学术文章
@zh-cn
1997年学术文章
@zh-hans
1997年学术文章
@zh-my
1997年学术文章
@zh-sg
1997年學術文章
@yue
1997年學術文章
@zh
1997年學術文章
@zh-hant
name
Structure of the multidrug res ...... microscopy and image analysis.
@en
Structure of the multidrug res ...... microscopy and image analysis.
@nl
type
label
Structure of the multidrug res ...... microscopy and image analysis.
@en
Structure of the multidrug res ...... microscopy and image analysis.
@nl
prefLabel
Structure of the multidrug res ...... microscopy and image analysis.
@en
Structure of the multidrug res ...... microscopy and image analysis.
@nl
P2093
P2860
P356
P1476
Structure of the multidrug res ...... microscopy and image analysis.
@en
P2093
Callaghan R
Higgins CF
Rosenberg MF
P2860
P304
10685-10694
P356
10.1074/JBC.272.16.10685
P407
P577
1997-04-01T00:00:00Z