Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis.
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Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane TargetingSphingolipid signaling in metabolic disordersBridging the gap between statistical and biological epistasis in Alzheimer's diseasePhosphoinositide kinase signaling controls ER-PM cross-talk.Membrane Tension Acts Through PLD2 and mTORC2 to Limit Actin Network Assembly During Neutrophil MigrationLoss of Ypk1, the yeast homolog to the human serum- and glucocorticoid-induced protein kinase, accelerates phospholipase B1-mediated phosphatidylcholine deacylationDown-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stressSphingolipid biosynthesis upregulation by TOR complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stressThe GARP complex is required for cellular sphingolipid homeostasis.Ist2 in the yeast cortical endoplasmic reticulum promotes trafficking of the amino acid transporter Bap2 to the plasma membrane.TORC1-regulated protein kinase Npr1 phosphorylates Orm to stimulate complex sphingolipid synthesis.Ltc1 is an ER-localized sterol transporter and a component of ER-mitochondria and ER-vacuole contacts.The yeast p5 type ATPase, spf1, regulates manganese transport into the endoplasmic reticulum.A neurotoxic glycerophosphocholine impacts PtdIns-4, 5-bisphosphate and TORC2 signaling by altering ceramide biosynthesis in yeastEvolutionarily conserved 5'-3' exoribonuclease Xrn1 accumulates at plasma membrane-associated eisosomes in post-diauxic yeast.Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae.Lipid and Alzheimer's disease genes associated with healthy aging and longevity in healthy oldest-old.ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress.Expression of the bacterial type III effector DspA/E in Saccharomyces cerevisiae down-regulates the sphingolipid biosynthetic pathway leading to growth arrest.TORC2-a new player in genome stabilityA role for eisosomes in maintenance of plasma membrane phosphoinositide levels.Sphingolipids and ceramides of mouse aqueous humor: Comparative profiles from normotensive and hypertensive DBA/2J mice.Systematic lipidomic analysis of yeast protein kinase and phosphatase mutants reveals novel insights into regulation of lipid homeostasis.TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids.Localization of lipid raft proteins to the plasma membrane is a major function of the phospholipid transfer protein Sec14.Regulation of mTOR activity in Snell dwarf and GH receptor gene-disrupted mice.Rom2-dependent phosphorylation of Elo2 controls the abundance of very long-chain fatty acids.Genome-wide association interaction analysis for Alzheimer's disease.Autophagy in the light of sphingolipid metabolismEisosomes are dynamic plasma membrane domains showing pil1-lsp1 heteroligomer binding equilibrium.Control of Plasma Membrane Permeability by ABC Transporters.Target of Rapamycin Complex 2 Regulates Actin Polarization and Endocytosis via Multiple Pathways.Eisosomes provide membrane reservoirs for rapid expansion of the yeast plasma membrane.Orm protein phosphoregulation mediates transient sphingolipid biosynthesis response to heat stress via the Pkh-Ypk and Cdc55-PP2A pathwaysEisosome Ultrastructure and Evolution in Fungi, Microalgae, and LichensCharacterization of AnNce102 and its role in eisosome stability and sphingolipid biosynthesis.PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.Saccharomyces cerevisiae Is Dependent on Vesicular Traffic between the Golgi Apparatus and the Vacuole When Inositolphosphorylceramide Synthase Aur1 Is Inactivated.Glycosphingolipids and cell death: one aim, many waysA Signaling Lipid Associated with Alzheimer's Disease Promotes Mitochondrial Dysfunction
P2860
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P2860
Plasma membrane stress induces relocalization of Slm proteins and activation of TORC2 to promote sphingolipid synthesis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Plasma membrane stress induces ...... romote sphingolipid synthesis.
@en
Plasma membrane stress induces ...... romote sphingolipid synthesis.
@nl
type
label
Plasma membrane stress induces ...... romote sphingolipid synthesis.
@en
Plasma membrane stress induces ...... romote sphingolipid synthesis.
@nl
prefLabel
Plasma membrane stress induces ...... romote sphingolipid synthesis.
@en
Plasma membrane stress induces ...... romote sphingolipid synthesis.
@nl
P2093
P2860
P50
P356
P1433
P1476
Plasma membrane stress induces ...... romote sphingolipid synthesis.
@en
P2093
Doris Berchtold
Isabelle Riezman
Manuele Piccolis
Nicolas Chiaruttini
Tobias C Walther
P2860
P2888
P304
P356
10.1038/NCB2480
P577
2012-04-15T00:00:00Z