PKCβ inhibition with ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes.
about
Contractile apparatus dysfunction early in the pathophysiology of diabetic cardiomyopathyDiabetic cardiomyopathy: bench to bedsideProtein kinase C mechanisms that contribute to cardiac remodellingMolecular dynamics approach to probe PKCβII-ligand interactions and influence of crystal water molecules on these interactions.Metabolic Remodeling in Diabetic Cardiomyopathy.Hyperglycemic and hyperlipidemic conditions alter cardiac cell biomechanical propertiesDeficiency of a lipid droplet protein, perilipin 5, suppresses myocardial lipid accumulation, thereby preventing type 1 diabetes-induced heart malfunctionN-acetylcysteine and allopurinol confer synergy in attenuating myocardial ischemia injury via restoring HIF-1α/HO-1 signaling in diabetic rats.Propofol Attenuates Small Intestinal Ischemia Reperfusion Injury through Inhibiting NADPH Oxidase Mediated Mast Cell ActivationReactive oxygen species signaling facilitates FOXO-3a/FBXO-dependent vascular BK channel β1 subunit degradation in diabetic mice.Effects of Glucose Concentration on Propofol Cardioprotection against Myocardial Ischemia Reperfusion Injury in Isolated Rat Hearts.RhoA/rock signaling mediates peroxynitrite-induced functional impairment of Rat coronary vesselsDiabetes-induced increased oxidative stress in cardiomyocytes is sustained by a positive feedback loop involving Rho kinase and PKCβ2.Agonist activated PKCβII translocation and modulation of cardiac myocyte contractile function.Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of DiabetesHyperglycemia-induced protein kinase C β2 activation induces diastolic cardiac dysfunction in diabetic rats by impairing caveolin-3 expression and Akt/eNOS signaling.Vimentin is a target of PKCβ phosphorylation in MCP-1-activated primary human monocytes.N-acetylcysteine attenuates myocardial dysfunction and postischemic injury by restoring caveolin-3/eNOS signaling in diabetic rats.Reactivation of fetal splicing programs in diabetic hearts is mediated by protein kinase C signaling.Inhibition of PKCβ2 overexpression ameliorates myocardial ischaemia/reperfusion injury in diabetic rats via restoring caveolin-3/Akt signaling.IRS proteins and diabetic complications.Antioxidant N-acetylcysteine attenuates the reduction of Brg1 protein expression in the myocardium of type 1 diabetic rats.Emerging roles of RNA-binding proteins in diabetes and their therapeutic potential in diabetic complications.Changes in mitochondrial morphology and organization can enhance energy supply from mitochondrial oxidative phosphorylation in diabetic cardiomyopathy.The Potential Role of Oxidative Stress in Cardiac Hypertrophy: A Narrative Review.Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4.Glycine Protects H9C2 Cardiomyocytes from High Glucose- and Hypoxia/Reoxygenation-Induced Injury via Inhibiting PKCβ2 Activation and Improving Mitochondrial Quality.Protein Kinase C Inhibition With Ruboxistaurin Increases Contractility and Reduces Heart Size in a Swine Model of Heart Failure With Reduced Ejection Fraction
P2860
Q26799594-139D52F7-C313-4EBA-8F90-5074D61A4A36Q26997062-152620A7-1DA6-4A88-AA84-7C51121CE1C4Q28075729-4F30E65E-7178-4A2A-9C03-EACD63CF0658Q30368334-5ECF2CE2-1F1C-4EB9-AA19-3C37E468F52DQ33623469-0547277A-BFEC-4FFF-9C5C-67F8E706652DQ33736504-7149C1FF-FB5F-4633-85CE-25DC417AD2B5Q33899819-5D4A31E9-3AF3-4E1B-972B-09F11267DC9CQ34852014-C5D067CF-4577-4758-B9B6-73CE070AD8C6Q35889755-34D9ECF9-7EE1-4052-B32C-D3F664DC39FEQ36047479-F8B7FB72-3867-4874-8F66-9B0F7D416D11Q36146266-A2684FC7-48C6-4B59-8190-48A398469C4CQ36159672-1889DF26-36F2-4E90-9C0F-C70F6EDE7933Q36312528-45E7562A-A2FA-4731-8AE7-6DDEF9158398Q36920937-55A39594-52E7-4F3F-9DED-3816DBDF16ADQ36984183-169DBB74-E0A7-4B76-ACA7-5459EC3BF6D3Q37015027-690E191D-3C31-45D5-8E2D-F5F132155582Q37319302-560C47A2-32D6-4B5F-8ABC-23FA0B6DB200Q37336736-09BC45A0-5F8B-40D4-9D36-D7EFAD0E7ECAQ37368686-1C27C312-C360-4F48-A34A-4FF14EADA3BDQ38890008-945C512D-D82D-4B1B-AEB9-562197DF1910Q38924963-1FCF7B1B-0297-4AB2-97A3-EFEC626220FAQ42128148-44451EC9-88E5-40AA-9009-1C13762DDF1BQ47252604-D014777C-B1A4-40BD-8585-C177108E8D59Q48052664-F0B5FEAA-E90A-445F-80D8-9720EDF4D9C0Q50052210-704F8D11-C47A-407B-867A-3BCD38B9A3AEQ50092600-8D4A68D7-007E-4174-96A9-C7DC39F34658Q55018528-B968CEE6-E981-4F9C-8236-BF574D1B8A7CQ57396450-BE49AA65-2909-4FFC-933B-1128CCDB8D67
P2860
PKCβ inhibition with ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfunction in rats with streptozotocin-induced diabetes.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh-hant
name
PKCβ inhibition with ruboxista ...... reptozotocin-induced diabetes.
@en
PKCβ inhibition with ruboxista ...... reptozotocin-induced diabetes.
@nl
type
label
PKCβ inhibition with ruboxista ...... reptozotocin-induced diabetes.
@en
PKCβ inhibition with ruboxista ...... reptozotocin-induced diabetes.
@nl
prefLabel
PKCβ inhibition with ruboxista ...... reptozotocin-induced diabetes.
@en
PKCβ inhibition with ruboxista ...... reptozotocin-induced diabetes.
@nl
P2093
P2860
P356
P1433
P1476
PKCβ inhibition with ruboxista ...... reptozotocin-induced diabetes.
@en
P2093
Gordon T Wong
Shaoqing Lei
Tingting Wang
Xiaowen Mao
Zhengyuan Xia
P2860
P304
P356
10.1042/CS20110176
P407
P577
2012-02-01T00:00:00Z