Mutagenic and genotoxic effects of three vinyl chloride-induced DNA lesions: 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 4-amino-5-(imidazol-2-yl)imidazole.
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Integrity of duplex structures without hydrogen bonding: DNA with pyrene paired at abasic sitesBasis of Miscoding of the DNA Adduct N2,3-Ethenoguanine by Human Y-family DNA PolymerasesReplication ofN2,3-Ethenoguanine by DNA PolymerasesAlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivoPolychlorinated Biphenyl (PCB) carcinogenicity with special emphasis on airborne PCBsA 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatchThe pyrimidine ring-opened derivative of 1,N6-ethenoadenine is excised from DNA by the Escherichia coli Fpg and Nth proteins.A novel role for transcription-coupled nucleotide excision repair for the in vivo repair of 3,N4-ethenocytosine.Chemical biology of mutagenesis and DNA repair: cellular responses to DNA alkylationBiological properties of single chemical-DNA adducts: a twenty year perspectiveDNA oligomers containing site-specific and stereospecific exocyclic deoxyadenosine adducts of 1,2,3,4-diepoxybutane: synthesis, characterization, and effects on DNA structure.Induction of frameshift and base pair substitution mutations by the major DNA adduct of the endogenous carcinogen malondialdehyde.Oxyradicals and DNA damage.Significance of multiple mutations in cancer.1,3-Butadiene-Induced Adenine DNA Adducts Are Genotoxic but Only Weakly Mutagenic When Replicated in Escherichia coli of Various Repair and Replication BackgroundsVinyl chloride: still a cause for concern.Endogenous versus exogenous DNA adducts: their role in carcinogenesis, epidemiology, and risk assessment.The benzene metabolite p-benzoquinone forms adducts with DNA bases that are excised by a repair activity from human cells that differs from an ethenoadenine glycosylase.Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway.A viral genome containing an unstable aflatoxin B1-N7-guanine DNA adduct situated at a unique siteMutational properties of the primary aflatoxin B1-DNA adduct.An organizational approach for the assessment of DNA adduct data in risk assessment: case studies for aflatoxin B1, tamoxifen and vinyl chloride.Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine.The generation of carcinogenic etheno-DNA adducts in the liver of patients with nonalcoholic fatty liver diseaseDifferential repair of etheno-DNA adducts by bacterial and human AlkB proteinsMutagenic potency of exocyclic DNA adducts: marked differences between Escherichia coli and simian kidney cells.DNA repair is indispensable for survival after acute inflammation.Vinyl chloride-a classical industrial toxicant of new interest.3,N4-ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase.Inhibition of DNA replication fork progression and mutagenic potential of 1, N6-ethenoadenine and 8-oxoguanine in human cell extracts.Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde.XRCC1 and base excision repair balance in response to nitric oxideOxidative stress-induced 1, N6-ethenodeoxyadenosine adduct formation contributes to hepatocarcinogenesis.Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins.Accelerated repair and reduced mutagenicity of DNA damage induced by cigarette smoke in human bronchial cells transfected with E.coli formamidopyrimidine DNA glycosylase.All four known cyclic adducts formed in DNA by the vinyl chloride metabolite chloroacetaldehyde are released by a human DNA glycosylaseMechanisms of lung tumorigenesis by ethyl carbamate and vinyl carbamate.Damage of DNA and proteins by major lipid peroxidation products in genome stability.The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adducts.
P2860
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P2860
Mutagenic and genotoxic effects of three vinyl chloride-induced DNA lesions: 1,N6-ethenoadenine, 3,N4-ethenocytosine, and 4-amino-5-(imidazol-2-yl)imidazole.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Mutagenic and genotoxic effect ...... no-5-(imidazol-2-yl)imidazole.
@en
Mutagenic and genotoxic effect ...... no-5-(imidazol-2-yl)imidazole.
@nl
type
label
Mutagenic and genotoxic effect ...... no-5-(imidazol-2-yl)imidazole.
@en
Mutagenic and genotoxic effect ...... no-5-(imidazol-2-yl)imidazole.
@nl
prefLabel
Mutagenic and genotoxic effect ...... no-5-(imidazol-2-yl)imidazole.
@en
Mutagenic and genotoxic effect ...... no-5-(imidazol-2-yl)imidazole.
@nl
P2093
P356
P1433
P1476
Mutagenic and genotoxic effect ...... no-5-(imidazol-2-yl)imidazole.
@en
P2093
Essigmann JM
Niedernhofer LJ
P304
12793-12801
P356
10.1021/BI00210A031
P407
P577
1993-11-01T00:00:00Z