A CD47-blocking TRAIL fusion protein with dual pro-phagocytic and pro-apoptotic anticancer activity.
about
C-type lectin-like molecule-1 (CLL1)-targeted TRAIL augments the tumoricidal activity of granulocytes and potentiates therapeutic antibody-dependent cell-mediated cytotoxicityUse of single chain antibody derivatives for targeted drug delivery.Programmed Death Ligand 1 (PD-L1)-targeted TRAIL combines PD-L1-mediated checkpoint inhibition with TRAIL-mediated apoptosis induction.CD20-selective inhibition of CD47-SIRPα “don't eat me” signaling with a bispecific antibody-derivative enhances the anticancer activity of daratumumab, alemtuzumab and obinutuzumab.CD47-ligation induced cell death in T-acute lymphoblastic leukemia.
P2860
A CD47-blocking TRAIL fusion protein with dual pro-phagocytic and pro-apoptotic anticancer activity.
description
2013 nî lūn-bûn
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2013年の論文
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name
A CD47-blocking TRAIL fusion p ...... apoptotic anticancer activity.
@en
A CD47-blocking TRAIL fusion p ...... apoptotic anticancer activity.
@nl
type
label
A CD47-blocking TRAIL fusion p ...... apoptotic anticancer activity.
@en
A CD47-blocking TRAIL fusion p ...... apoptotic anticancer activity.
@nl
prefLabel
A CD47-blocking TRAIL fusion p ...... apoptotic anticancer activity.
@en
A CD47-blocking TRAIL fusion p ...... apoptotic anticancer activity.
@nl
P2093
P2860
P356
P1476
A CD47-blocking TRAIL fusion p ...... apoptotic anticancer activity.
@en
P2093
Douwe F Samplonius
Jurjen Gerssen
Robert J van Ginkel
Valerie R Wiersma
Wijnand Helfrich
P2860
P304
P356
10.1111/BJH.12617
P407
P577
2013-10-26T00:00:00Z