Hepatic Smad7 overexpression causes severe iron overload in mice.

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Hepatic Smad7 overexpression causes severe iron overload in mice.

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2017 nî lūn-bûn

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Hepatic Smad7 overexpression causes severe iron overload in mice.

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Hepatic Smad7 overexpression causes severe iron overload in mice.

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Hepatic Smad7 overexpression causes severe iron overload in mice.

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Hepatic Smad7 overexpression causes severe iron overload in mice.

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Hepatic Smad7 overexpression causes severe iron overload in mice.

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Hepatic Smad7 overexpression causes severe iron overload in mice.

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P1476

Hepatic Smad7 overexpression causes severe iron overload in mice.

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P2093

Andreas Teufel

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Dilay Lai

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Feng Teng

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Julia Werle

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Maja Vujić Spasić

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Martina U Muckenthaler

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Seddik Hammad

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Steven Dooley

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Thorsten Maas

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P2860

Smad7 antagonizes transforming growth factor beta signaling in the nucleus by interfering with functional Smad-DNA complex formation

Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload

Hepcidin expression in the liver: relatively low level in patients with chronic hepatitis C

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

Iron homeostasis in host defence and inflammation

Transforming growth factor beta1 induces nuclear export of inhibitory Smad7

Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload

A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression

Perturbation of hepcidin expression by BMP type I receptor deletion induces iron overload in mice

Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe

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581-585

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scholarly article

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10.1182/BLOOD-2017-07-796797

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English

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P478

131

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P577

2017-12-13T00:00:00Z

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P698

29237592

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P921

overexpression

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5843805

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