Antisense oligonucleotide-induced exon skipping across the human dystrophin gene transcript.
about
Enhanced exon-skipping induced by U7 snRNA carrying a splicing silencer sequence: Promising tool for DMD therapyAntisense-mediated exon skipping: a versatile tool with therapeutic and research applicationsSplicing therapy for neuromuscular diseaseAntisense oligonucleotide induced exon skipping and the dystrophin gene transcript: cocktails and chemistriesProgress toward therapy with antisense-mediated splicing modulationAntisense PMO found in dystrophic dog model was effective in cells from exon 7-deleted DMD patientTargeted skipping of human dystrophin exons in transgenic mouse model systemically for antisense drug developmentDynamics of co-transcriptional pre-mRNA folding influences the induction of dystrophin exon skipping by antisense oligonucleotides.Proteomic profiling of antisense-induced exon skipping reveals reversal of pathobiochemical abnormalities in dystrophic mdx diaphragm.Guanine analogues enhance antisense oligonucleotide-induced exon skipping in dystrophin gene in vitro and in vivo.Dystrophic Cardiomyopathy-Potential Role of Calcium in Pathogenesis, Treatment and Novel TherapiesRational design of antisense oligomers to induce dystrophin exon skipping.Design and evaluation of locked nucleic acid-based splice-switching oligonucleotides in vitro.Mismatched single stranded antisense oligonucleotides can induce efficient dystrophin splice switching.The FSHD atrophic myotube phenotype is caused by DUX4 expression.Nonsense mutation-associated Becker muscular dystrophy: interplay between exon definition and splicing regulatory elements within the DMD gene.Therapeutic exon skipping for dysferlinopathies?In-frame dystrophin following exon 51-skipping improves muscle pathology and function in the exon 52-deficient mdx mouse.Personalized exon skipping strategies to address clustered non-deletion dystrophin mutations.Antisense therapy in neurologyALS-associated FUS mutations result in compromised FUS alternative splicing and autoregulation.Pip5 transduction peptides direct high efficiency oligonucleotide-mediated dystrophin exon skipping in heart and phenotypic correction in mdx mice.Antisense oligonucleotide induction of progerin in human myogenic cellsLarge Genomic Deletions in CACNA1A Cause Episodic Ataxia Type 2Clinical phenotypes as predictors of the outcome of skipping around DMD exon 45.In silico screening based on predictive algorithms as a design tool for exon skipping oligonucleotides in Duchenne muscular dystrophyNon-sequential and multi-step splicing of the dystrophin transcript.Deletion of Dystrophin In-Frame Exon 5 Leads to a Severe Phenotype: Guidance for Exon Skipping Strategies.Pseudoexon activation increases phenotype severity in a Becker muscular dystrophy patient.A prospective study in the rational design of efficient antisense oligonucleotides for exon skipping in the DMD gene.Multiple exon skipping strategies to by-pass dystrophin mutations.Targeted exon skipping to address "leaky" mutations in the dystrophin gene.Novel compounds for the treatment of Duchenne muscular dystrophy: emerging therapeutic agentsMolecular-targeted therapy for Duchenne muscular dystrophy: progress and potential.Gene therapy for muscular dystrophy: current progress and future prospects.Progress in therapeutic antisense applications for neuromuscular disorders.Targeted exon skipping to correct exon duplications in the dystrophin gene.Exon skipping for nonsense mutations in Duchenne muscular dystrophy: too many mutations, too few patients?Design of phosphorodiamidate morpholino oligomers (PMOs) for the induction of exon skipping of the human DMD gene.Guidelines for antisense oligonucleotide design and insight into splice-modulating mechanisms.
P2860
Q24631244-80BA1AE1-72C0-4E3B-8B14-27E92727B738Q24682555-463BE9C9-67B2-4B74-A4E5-FC0A9EF12D3EQ27009581-FB993A55-A09B-4AB3-82FD-D904154A624AQ27480935-4B588306-47C1-4C86-AFC5-103CE8670CBDQ27489807-82ADF478-A934-4CC7-B68F-7EEE63AF1FE2Q28475196-DABA9E58-44D2-499A-8361-A9DB2D982AC8Q28478166-5681C41D-EBCE-4780-9F61-3430566A1770Q33325470-C7DC7DB4-1A92-46BF-8FDE-AB342D33B500Q33398588-8676E949-23F6-40DD-8932-607CBF1FA3E9Q33525253-0CD29062-C1E5-4AAC-9817-D72CD4C846F3Q33608478-D2566F97-41EA-4BC0-86FF-A4A9CFDB0050Q33713852-5B268C5F-9FCC-45E8-B6B4-C9E306F07A8EQ33843195-6ED12E4A-1BCA-4474-BF77-D53701817236Q34052338-2C721039-DBC0-4891-8574-B784542AB308Q34067055-CD2CED29-D6A9-4694-85ED-647265A70C23Q34221402-3076B734-0621-45FF-96C3-BC15790FC7FEQ34329418-9DE9BA42-7C25-4E28-AB03-4A97D1D366A1Q34343780-7429672D-25D9-483F-B205-331910F5B4D6Q34349200-CA520072-FB07-425C-8B45-CC44A1310A49Q34608717-87DF0D61-EEF4-44BD-ACA2-78D1B5906607Q35034350-AFDF64F9-1FB7-41DA-BD97-A7042546909FQ35084227-46E68877-3991-4359-BF55-A371EC240F8BQ35180565-8C18B56B-58EF-48AA-825A-4D5B3CCFF36BQ35204801-3C3EED4B-F853-4D6F-8393-094C4356CB03Q35224393-7751CD2E-24A6-404D-B6BE-067005484EE9Q35588627-F1DE0668-59A8-4D51-8EDC-C303D85E4D83Q35869261-CA2C8AEA-ADB4-40C9-8E33-CB715A4B153AQ35888871-F79EA7A0-F6D1-4043-B102-1D0132EAA64BQ35907748-0E627B03-46EE-4E6F-A27B-4123C078267EQ36114216-7B6CF831-E06D-4ACE-AE04-9DB9E6D1682EQ36369845-5C3CAFFA-F0C2-4317-B487-B6D9C6396684Q36403759-5EA1E59E-E8DC-48A4-835E-D0B72190851EQ36925191-A04C7D04-7260-4AE3-AF45-BF9BF3D099B3Q37142004-EEFB69BD-29D3-4816-B5A0-BE14C9B7DF42Q37519650-2A743376-9793-4428-8172-D381B8DA44E9Q37609948-94139FB0-D9AE-45A4-9E06-E79C99A262CBQ37695543-F1AEAA5C-8851-4334-ABD9-6EB4BC7EC8A0Q38014906-121F99EF-F958-4C2D-9761-4ED3B804F9E4Q38357434-01764AEC-DAD6-41B3-9E51-D17E13CFCF0BQ38360555-109FFC30-79F5-4F16-AF1F-6E6C07C4FF5C
P2860
Antisense oligonucleotide-induced exon skipping across the human dystrophin gene transcript.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Antisense oligonucleotide-indu ...... an dystrophin gene transcript.
@en
Antisense oligonucleotide-indu ...... an dystrophin gene transcript.
@nl
type
label
Antisense oligonucleotide-indu ...... an dystrophin gene transcript.
@en
Antisense oligonucleotide-indu ...... an dystrophin gene transcript.
@nl
prefLabel
Antisense oligonucleotide-indu ...... an dystrophin gene transcript.
@en
Antisense oligonucleotide-indu ...... an dystrophin gene transcript.
@nl
P2093
P356
P1433
P1476
Antisense oligonucleotide-indu ...... man dystrophin gene transcript
@en
P2093
Abbie M Fall
Catherine Coleman
Graham McClorey
Penny L Harding
Steve D Wilton
P304
P356
10.1038/SJ.MT.6300095
P50
P577
2007-02-06T00:00:00Z