about
Cell death triggered by a novel mutation in the alphaA-crystallin gene underlies autosomal dominant cataract linked to chromosome 21qCloning, expression, and chaperone-like activity of human alphaA-crystallinThe molecular chaperone alphaA-crystallin enhances lens epithelial cell growth and resistance to UVA stressIn vivo substrates of the lens molecular chaperones αA-crystallin and αB-crystallinAlpha-crystallin expression affects microtubule assembly and prevents their aggregationReduced survival of lens epithelial cells in the alphaA-crystallin-knockout mouseMechanism of small heat shock protein function in vivo: a knock-in mouse model demonstrates that the R49C mutation in alpha A-crystallin enhances protein insolubility and cell deathPharmacological chaperone for α-crystallin partially restores transparency in cataract modelsAlphaA-crystallin R49Cneo mutation influences the architecture of lens fiber cell membranes and causes posterior and nuclear cataracts in mice.Difference in phototoxicity of cyclodextrin complexed fullerene [(gamma-CyD)2/C60] and its aggregated derivatives toward human lens epithelial cells.αA-Crystallin associates with α6 integrin receptor complexes and regulates cellular signaling.A knock-in mouse model for the R120G mutation of αB-crystallin recapitulates human hereditary myopathy and cataracts.Inhibition of lens photodamage by UV-absorbing contact lenses.Phototoxicity and cytotoxicity of fullerol in human lens epithelial cellsImmunological detection of N-formylkynurenine in porphyrin-mediated photooxided lens α-crystallin.Comparative proteomic analysis identifies age-dependent increases in the abundance of specific proteins after deletion of the small heat shock proteins αA- and αB-crystallin.Mechanism of insolubilization by a single-point mutation in alphaA-crystallin linked with hereditary human cataracts.p62 expression and autophagy in αB-crystallin R120G mutant knock-in mouse model of hereditary cataract.Effects of alpha-crystallin on lens cell function and cataract pathology.Identification of genes responsive to UV-A radiation in human lens epithelial cells using complementary DNA microarrays.Evaluation of the toxicity of triamcinolone acetonide and dexamethasone sodium phosphate on human lens epithelial cells (HLE B-3).Peroxide resistance in human and mouse lens epithelial cell lines is related to long-term changes in cell biology and architecture.In vivo lens deficiency of the R49C alphaA-crystallin mutant.Differential protective activity of alpha A- and alphaB-crystallin in lens epithelial cells.Effect of ultraviolet-B radiation on protein synthesis in cultured lens epithelial cells.Autophagy and UPR in alpha-crystallin mutant knock-in mouse models of hereditary cataractsActivation of the unfolded protein response by a cataract-associated αA-crystallin mutation.Mimicking phosphorylation of the small heat-shock protein alphaB-crystallin recruits the F-box protein FBX4 to nuclear SC35 speckles.Cell kinetic status of mouse lens epithelial cells lacking alphaA- and alphaB-crystallin.A comparative analysis of alphaA- and alphaB-crystallin expression during the cell cycle in primary mouse lens epithelial cultures.Probing the changes in gene expression due to α-crystallin mutations in mouse models of hereditary human cataract.Expression of recombinant bovine gamma B-, gamma C- and gamma D-crystallins and correlation with native proteins.Lens hexokinase deactivation by near-UV irradiationSpectroscopic studies on the riboflavin-sensitized conformational changes of calf lens alpha-crystallinConformational changes of beta H-crystallin in riboflavin-sensitized photooxidationPhotoreactions of human lens monomeric crystallinsChange in sulfhydryl group microenvironment of calf lens alpha-crystallin by 300 nm lightFluorescence studies on the age related changes in bovine and human lens membrane structureConformational changes of bovine lens crystallins in a photodynamic systemThe effects of near-UV radiation on human lens beta-crystallins: protein structural changes and the production of O2- and H2O2
P50
Q24295954-CD289EB4-9033-4642-A39F-DD4287B8578FQ24323875-5C304CE8-54FB-4FD3-AE3F-0223751196DDQ28504935-0AB10634-5390-4418-9E84-7D1BB608C0AFQ28538157-070C74C3-92E5-44C7-9466-4FCB6318D448Q28585733-91F71C12-D3AE-4D6D-90F0-4267266E5A88Q28588245-E9309F03-5351-4FEB-A6E3-7987DC002415Q28591145-6999D004-2806-4BA0-ACDC-D1EFFA1AC1F1Q30700509-0A83BEBD-9D84-47F8-A4A1-60B91CF1DFD7Q33484430-972B6505-CA5C-41B4-8259-DE1335C39D01Q33565924-7DABC9C3-C3D3-4EC7-9068-BEE13CB735F7Q34233267-0D4B78B8-CF7E-4D7A-9D45-9B05C708B211Q34699001-90E10E2A-D8BD-4946-A7D8-14AB26A08B3EQ35523992-1E830E45-3519-4B67-A803-5BE3930BC174Q36606861-A3037319-2FBD-4283-9843-E56C98A5C550Q36687573-B62FD6E6-B781-4397-BFE0-5C4BF3FF99B9Q36949590-364D5443-106A-4C29-B7E6-36F0526E8E12Q37097757-DE035CB4-7A39-400A-9F2F-CC02A1E0DEEFQ37227740-EBD960E8-C159-4E7C-8AB8-09502E4EF831Q37622325-34C1C6C8-E837-4AE5-B126-6BC25B5FDA78Q38337214-FE3B0285-0901-48B5-A126-8B1EE612D0BFQ39541899-B8413263-3E03-459F-B420-94F48CBCAC33Q40383775-970AA1AC-0917-4EE4-8470-A6ABB9FE4CA3Q40640833-0A1AC41E-E8C6-4D5E-8BAB-A997D71CA484Q40857765-357A8040-34C3-42B3-A11B-54F5AD51A421Q41716923-E6F3A72F-1859-47A4-AC7A-5C7BC5F427DCQ42121573-1E84CCCE-FFA5-4186-99DE-FAB1A0A6F8D1Q42408572-B026B4C3-507F-4001-8603-221D821FAB35Q45128868-CF6101E5-890B-474C-93A2-B98AA1E10394Q45150717-2923E9DF-2B55-4853-A804-C5B9DE4D626DQ45218336-3D112471-B43F-4A58-9DAA-7BB7AA96C4FCQ47714691-701CA74F-668F-4599-915A-0645A541423AQ48083077-95706026-52AD-49CD-AA1B-9D7FEC77F36BQ68324296-C63C7A67-D3FD-419E-8D26-265F3A7A514FQ68412006-C6E22CC9-23AB-4510-B2B3-045DCDCD9354Q68486363-1DEFE64D-AEE1-4EB6-8C1C-4105135C5F7AQ69354603-1950A4EF-BB68-4697-B4D7-55185D48C99CQ69499661-78CBCB41-FFED-4E1B-B34B-59887CA88191Q69586697-9FEEF3F8-76F2-41C3-9366-9CBC54BBAC02Q69600829-30448E6B-8FDC-4E1F-9BE4-14761704DFECQ69685166-2F608778-E462-4B7D-BD5C-6985F88527B9
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Usha P. Andley
@ast
Usha P. Andley
@en
Usha P. Andley
@es
Usha P. Andley
@nl
Usha P. Andley
@sl
type
label
Usha P. Andley
@ast
Usha P. Andley
@en
Usha P. Andley
@es
Usha P. Andley
@nl
Usha P. Andley
@sl
prefLabel
Usha P. Andley
@ast
Usha P. Andley
@en
Usha P. Andley
@es
Usha P. Andley
@nl
Usha P. Andley
@sl
P106
P1153
7005301015
P31
P496
0000-0001-7049-7591