about
Cutting edge: The transcription factor eomesodermin enables CD8+ T cells to compete for the memory cell niche.Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cellsTechnical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes.Network analysis reveals centrally connected genes and pathways involved in CD8+ T cell exhaustion versus memory.From mechanism to therapies in systemic lupus erythematosus.Cutting Edge: B Cell-Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection.Progenitor and terminal subsets of CD8+ T cells cooperate to contain chronic viral infection.Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection.TCF-1 flips the switch on Eomes.IFN-gamma mediates the death of Th1 cells in a paracrine manner.Viral MHCI inhibition evades tissue-resident memory T cell formation and responses
P50
Q34286922-EA5F0C76-1B2B-4AE9-A18D-FFA54015BE26Q35824223-241A3539-89F5-46A4-A8B0-E5A13FEB7BFBQ36534837-FB4EE507-4004-49A2-87D9-7B23AEEE22AFQ37110140-E929A8EB-EB94-4090-9BCA-C310A5FE3AD0Q39101063-E592BFF1-D1ED-4FC9-9684-9AC6D46C3AD8Q39588420-69A3A8FA-6A5E-4242-B0D8-20AE3595A2D0Q40695934-0DD1D091-D939-4775-BCEE-FA635CFFFE0BQ41825142-C2BF6DF8-7849-45C5-8CBC-3063466FC45BQ51040002-8FDC9596-7287-4CE7-8D63-5C9BF4E24E11Q51968174-67E2ACB8-3CBF-4B29-A6F8-FCD85714FC51Q94219957-A72AFE62-C2EE-4A61-A0D4-0A5F0716F9F0
P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Michael A Paley
@ast
Michael A Paley
@en
Michael A Paley
@es
Michael A Paley
@nl
Michael A Paley
@sl
type
label
Michael A Paley
@ast
Michael A Paley
@en
Michael A Paley
@es
Michael A Paley
@nl
Michael A Paley
@sl
prefLabel
Michael A Paley
@ast
Michael A Paley
@en
Michael A Paley
@es
Michael A Paley
@nl
Michael A Paley
@sl
P106
P31
P496
0000-0001-8724-3176