Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.
about
Chronic Glutamate Toxicity in Neurodegenerative Diseases-What is the Evidence?Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signalingHigh-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma CellsNigral proteasome inhibition in mice leads to motor and non-motor deficits and increased expression of Ser129 phosphorylated α-synucleinThe cystine/glutamate antiporter system x(c)(-) in health and disease: from molecular mechanisms to novel therapeutic opportunities.Redox-based therapeutics in neurodegenerative disease.Non-cell autonomous influence of the astrocyte system xc- on hypoglycaemic neuronal cell death.Impaired long-term potentiation and long-term memory deficits in xCT-deficient sut mice.A Cytotoxic, Co-operative Interaction Between Energy Deprivation and Glutamate Release From System xc- Mediates Aglycemic Neuronal Cell DeathThiol-redox signaling, dopaminergic cell death, and Parkinson's diseaseInterleukin 1β Regulation of the System xc- Substrate-specific Subunit, xCT, in Primary Mouse Astrocytes Involves the RNA-binding Protein HuRAbsence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis.Caloric Restriction Protects against Lactacystin-Induced Degeneration of Dopamine Neurons Independent of the Ghrelin Receptor.Main path and byways: non-vesicular glutamate release by system xc(-) as an important modifier of glutamatergic neurotransmission.Emerging roles of system [Formula: see text] antiporter and its inhibition in CNS disorders.Mutation of ataxia-telangiectasia mutated is associated with dysfunctional glutathione homeostasis in cerebellar astroglia.l-DOPA-induced dyskinesia and neuroinflammation: do microglia and astrocytes play a role?1,2,3,4,6-penta-O-galloyl-β-D-glucose protects PC12 Cells from MPP(+)-mediated cell death by inducing heme oxygenase-1 in an ERK- and Akt-dependent manner.The role of Ca2+ in cell death caused by oxidative glutamate toxicity and ferroptosis.Extracellular glutamate: functional compartments operate in different concentration ranges.Comparative analysis of antibodies to xCT (Slc7a11): Forewarned is forearmed.Cystathionine is a novel substrate of cystine/glutamate transporter: implications for immune function.Sample collection and amino acids analysis of extracellular fluid of mouse brain slices with low flow push-pull perfusion.System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.Development of a primary microglia screening assay and its use to characterize inhibition of system xc- by erastin and its analogs.Implication of the glutamate-cystine antiporter xCT in schizophrenia cases linked to impaired GSH synthesis.Extrasynaptic glutamate release through cystine/glutamate antiporter contributes to ischemic damageFerroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease.Decreased reproductive performance in xCT-knockout male mice.Gestational exposure to inorganic arsenic (iAs3+) alters glutamate disposition in the mouse hippocampus and ionotropic glutamate receptor expression leading to memory impairment.Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model.Transport of BMAA into Neurons and Astrocytes by System xc.Physiology of Astroglia.Determining striatal extracellular glutamate levels in xCT mutant mice using LFPS CE-LIFKetamine Does Not Exert Protective Properties on Dopaminergic Neurons in the Lactacystin Mouse Model of Parkinson's Disease
P2860
Q26770781-F77E5F3B-10D6-4695-BF39-8B131BA5F493Q26864995-837EBCEF-1B02-45E3-B4F3-51EAB33A4D2BQ28547125-F29E243F-11EF-4782-8A01-30FFA08C1BB3Q30633819-8E5B34BE-DF27-4A86-9A7C-52BE7DD219FAQ34279067-34F872E9-FAC4-44A4-BFFF-4C3165D108BBQ34535918-58245AE0-A688-4829-B63F-2290D092C822Q35744426-5ECDFB76-40F1-4845-B3C6-233DEF18026CQ35861876-EB8122A0-3D5D-4135-A038-D2D656EC3015Q36271038-36891F1B-3383-4DD6-8FBC-3B57FFD0FD1EQ36326535-6D9A2841-0216-4060-87A6-F339E93BE023Q36489257-5072564E-9888-4E73-90B8-64F567326DC6Q37586538-57D3FB18-CEE0-464D-A070-6AC8044B0E67Q37729142-22D243D2-6651-49EA-8FDD-8CD100224AD9Q38580123-A02A10BA-BD1F-4923-BDC6-A96FC9E3E54DQ38618048-3A4BFBEF-52AA-4377-8A9E-F6382F1ABD7CQ38953210-71984973-15BC-4263-AC45-0331761214A7Q39012371-15182AF7-851A-466E-A2EF-F84909C2F8ABQ39257847-37F51B11-3254-45B7-AD38-43C5D6AAEF41Q39330890-A222F3B6-E9F5-450D-A294-2738C479F509Q40255443-E62469B8-0D3C-4B4C-9915-7779D30719CFQ40400682-49F90592-030D-4ED9-848F-D44E64D7FE69Q40403025-057AF311-860A-428B-BFD3-8842AC73AE8EQ40615766-6F0F23A9-8BDF-4887-AC8D-91A97920113EQ40961556-B0E93747-1F42-4A85-B398-5B6E2C0EA00EQ41682361-F9788440-C020-41F9-8B85-60A464BFB746Q41701597-410BE475-4857-42EE-8F35-D51DCE42F062Q42592261-487E7691-6D8A-4E3B-87D7-E11EB3612444Q46292537-E2473781-7500-4675-B08D-7CBE030DEF88Q47704898-4141F026-9B70-4A02-BC23-2F331E34A37FQ47769743-84DEB5C7-7595-4BAD-A41E-9B2717E4BAD2Q47775588-961390B5-78ED-439C-B078-FB68162F1308Q48194642-51751D6F-6D84-4EBE-83E3-2CC68B90EF3FQ49917383-EE1884D7-B254-4B98-A418-54D5F4002CB9Q56929402-85E28ACA-37F0-4488-AC49-C31D9AB3432AQ57072471-4F1D6E4B-7FE6-4EDB-ABC0-3E3A9BDAB8E6
P2860
Dopaminergic neurons of system x(c)⁻-deficient mice are highly protected against 6-hydroxydopamine-induced toxicity.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Dopaminergic neurons of system x
@nl
Dopaminergic neurons of system ...... roxydopamine-induced toxicity.
@en
type
label
Dopaminergic neurons of system x
@nl
Dopaminergic neurons of system ...... roxydopamine-induced toxicity.
@en
prefLabel
Dopaminergic neurons of system x
@nl
Dopaminergic neurons of system ...... roxydopamine-induced toxicity.
@en
P2093
P50
P356
P1433
P1476
Dopaminergic neurons of system ...... droxydopamine-induced toxicity
@en
P2093
Anneleen Schallier
Heike Beck
Hideyo Sato
Katia Vermoesen
Nikolaus Plesnila
Ruani Fernando
Seong Woong Kim
Shiro Bannai
Sho Kobayashi
Yvette Michotte
P304
P356
10.1096/FJ.10-177212
P407
P577
2010-12-29T00:00:00Z