about
Gastrointestinal tract and the mucosal macrophage reservoir in HIV infectionAccelerated lymphocyte reconstitution and long-term recovery after transplantation of lentiviral-transduced rhesus CD34+ cells mobilized by G-CSF and plerixaforMassive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infectionDevelopment of an acute and highly pathogenic nonhuman primate model of Nipah virus infection.CD4 T cell subsets in the mucosa are CD28+Ki-67-HLA-DR-CD69+ but show differential infection based on alpha4beta7 receptor expression during acute SIV infection.Characterization of subsets of CD4+ memory T cells reveals early branched pathways of T cell differentiation in humans.Resting naive CD4+ T cells are massively infected and eliminated by X4-tropic simian-human immunodeficiency viruses in macaquesHIV Gag protein conjugated to a Toll-like receptor 7/8 agonist improves the magnitude and quality of Th1 and CD8+ T cell responses in nonhuman primates.Infectious molecular clones from a simian immunodeficiency virus-infected rapid-progressor (RP) macaque: evidence of differential selection of RP-specific envelope mutations in vitro and in vivoLoss and dysregulation of Th17 cells during HIV infection.Expansion or depletion of T follicular helper cells during HIV infection: consequences for B cell responses.Genetic immunization in the lung induces potent local and systemic immune responses.Immune system development during early childhood in tropical Latin America: evidence for the age-dependent down regulation of the innate immune responseRhesus macaque lymph node PD-1(hi)CD4+ T cells express high levels of CXCR5 and IL-21 and display a CCR7(lo)ICOS+Bcl6+ T-follicular helper (Tfh) cell phenotype.Early short-term antiretroviral therapy is associated with a reduced prevalence of CD8(+)FoxP3(+) T cells in simian immunodeficiency virus-infected controller rhesus macaques.Suppression of transforming growth factor β receptor 2 and Smad5 is associated with high levels of microRNA miR-155 in the oral mucosa during chronic simian immunodeficiency virus infection.Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cellsImmunization of rabbits with highly purified, soluble, trimeric human immunodeficiency virus type 1 envelope glycoprotein induces a vigorous B cell response and broadly cross-reactive neutralization.Significant mobilization of both conventional and regulatory T cells with AMD3100.Mucosal and peripheral Lin- HLA-DR+ CD11c/123- CD13+ CD14- mononuclear cells are preferentially infected during acute simian immunodeficiency virus infection.SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection.Estimating the infectivity of CCR5-tropic simian immunodeficiency virus SIV(mac251) in the gut.Keratinocyte growth factor augments immune reconstitution after autologous hematopoietic progenitor cell transplantation in rhesus macaquesVaccination preserves CD4 memory T cells during acute simian immunodeficiency virus challengeToll-like receptor agonists influence the magnitude and quality of memory T cell responses after prime-boost immunization in nonhuman primatesReduced protection from simian immunodeficiency virus SIVmac251 infection afforded by memory CD8+ T cells induced by vaccination during CD4+ T-cell deficiency.Differentially expressed genes in MHC-compatible rat strains that are susceptible or resistant to experimental autoimmune uveitis.Suppressed Th17 levels correlate with elevated PIAS3, SHP2, and SOCS3 expression in CD4 T cells during acute simian immunodeficiency virus infection.Antiretroviral therapy prior to acute viral replication preserves CD4 T cells in the periphery but not in rectal mucosa during acute simian immunodeficiency virus infection.Estimating the impact of vaccination on acute simian-human immunodeficiency virus/simian immunodeficiency virus infections.Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infectionHigh frequencies of resting CD4+ T cells containing integrated viral DNA are found in rhesus macaques during acute lentivirus infections.Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection.Anti-retroviral therapy fails to restore the severe Th-17: Tc-17 imbalance observed in peripheral blood during simian immunodeficiency virus infection.Acute HIV infection: it takes more than guts.HIV vaccines: can mucosal CD4 T cells be protected?Mucosa and vaccine-induced immune protection in nonhuman primates.Prior Exposure to Zika Virus Significantly Enhances Peak Dengue-2 Viremia in Rhesus Macaques.Early treatment with reverse transcriptase inhibitors significantly suppresses peak plasma IFNα in vivo during acute simian immunodeficiency virus infection.Significant Depletion of CD4(+) T Cells Occurs in the Oral Mucosa during Simian Immunodeficiency Virus Infection with the Infected CD4(+) T Cell Reservoir Continuing to Persist in the Oral Mucosa during Antiretroviral Therapy.
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Joseph J Mattapallil
@ast
Joseph J Mattapallil
@en
Joseph J Mattapallil
@es
Joseph J Mattapallil
@nl
type
label
Joseph J Mattapallil
@ast
Joseph J Mattapallil
@en
Joseph J Mattapallil
@es
Joseph J Mattapallil
@nl
prefLabel
Joseph J Mattapallil
@ast
Joseph J Mattapallil
@en
Joseph J Mattapallil
@es
Joseph J Mattapallil
@nl
P106
P21
P31
P496
0000-0002-7412-9507