CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas
about
Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number.Fusion with extracellular domain of cytotoxic T-lymphocyte-associated-antigen 4 leads to enhancement of immunogenicity of Hantaan virus DNA vaccines in C57BL/6 mice.CTLA-4 blockade decreases TGF-beta, IDO, and viral RNA expression in tissues of SIVmac251-infected macaques.Transduction of the cytoplasmic domain of CTLA-4 inhibits TcR-specific activation signals and prevents collagen-induced arthritis.CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms.Intracellular concentrations of Ca(2+) modulate the strength of signal and alter the outcomes of cytotoxic T-lymphocyte antigen-4 (CD152)-CD80/CD86 interactions in CD4(+) T lymphocytes.
P2860
CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas
description
article
@en
im Februar 2006 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в лютому 2006
@uk
name
CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas
@en
CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas
@nl
type
label
CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas
@en
CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas
@nl
prefLabel
CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas
@en
CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas
@nl
P2093
P2860
P1476
CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas
@en
P2093
Bernhard Manger
Franziska G Matzkies
Joachim R Kalden
Martina Rahmeh
Thomas Nagel
P2860
P356
10.1111/J.1440-1711.2005.01402.X
P407
P577
2006-02-01T00:00:00Z