Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney
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Epigenetic regulation of caloric restriction in agingExpression of p16(INK4a) in peripheral blood T-cells is a biomarker of human agingTherapeutic targeting of replicative immortalityReproductive Aging Drives Protein Accumulation in the Uterus and Limits Lifespan in C. elegansSenescence and the pro-tumorigenic stromaJDP2 (Jun Dimerization Protein 2)-deficient mouse embryonic fibroblasts are resistant to replicative senescenceDefining the toxicology of agingAltered lipid metabolism in the aging kidney identified by three layered omic analysisInk4a/Arf expression is a biomarker of agingAccelerated senescence in kidneys of low-birth-weight rats after catch-up growthHyperglycemia causes cellular senescence via a SGLT2- and p21-dependent pathway in proximal tubules in the early stage of diabetic nephropathy.AGEMAP: a gene expression database for aging in miceTelomere shortening reduces regenerative capacity after acute kidney injury.The association between age and nephrosclerosis on renal biopsy among healthy adultsp16(INK4a) suppression by glucose restriction contributes to human cellular lifespan extension through SIRT1-mediated epigenetic and genetic mechanisms.Quantitative digital in situ senescence-associated β-galactosidase assayIonizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status.Proteins induced by telomere dysfunction are associated with human IgA nephropathy.Two functionally distinct isoforms of TL1A (TNFSF15) generated by differential ectodomain sheddingMonitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.INK4a knockout mice exhibit increased fibrosis under normal conditions and in response to unilateral ureteral obstruction.CYP24A1 exacerbated activity during diabetes contributes to kidney tubular apoptosis via caspase-3 increased expression and activation.Regulation of senescence in cancer and aging.Senotherapy: growing old and staying young?Pre-transplant CDKN2A expression in kidney biopsies predicts renal function and is a future component of donor scoring criteriaIn vivo and in vitro analysis of age-associated changes and somatic cellular senescence in renal epithelial cells.What determines ageing of the transplanted liver?The role of microRNAs in cellular senescence and age-related conditions of cartilage and bone.Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho miceINK4a deletion results in improved kidney regeneration and decreased capillary rarefaction after ischemia-reperfusion injury.Novel ARF/p53-independent senescence pathways in cancer repression.The Inflammatory Transcription Factors NFκB, STAT1 and STAT3 Drive Age-Associated Transcriptional Changes in the Human KidneyElevated p16ink4a Expression in Human Labial Salivary Glands as a Potential Correlate of Cognitive Aging in Late MidlifeA common variant of the p16(INK4a) genetic region is associated with physical function in older people.Diet and aging.DNA damage, cellular senescence and organismal ageing: causal or correlative?Effects of rhein lysinate on D-galactose-induced aging mice.Renal dopamine and angiotensin II receptor signaling in age-related hypertension.Assessing cell and organ senescence biomarkersThe Expression Changes of Inflammasomes in the Aging Rat Kidneys.
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Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney
description
article
@en
im Februar 2004 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в лютому 2004
@uk
name
Expression of p16INK4a and oth ...... ed genes in aging human kidney
@en
Expression of p16INK4a and oth ...... ed genes in aging human kidney
@nl
type
label
Expression of p16INK4a and oth ...... ed genes in aging human kidney
@en
Expression of p16INK4a and oth ...... ed genes in aging human kidney
@nl
prefLabel
Expression of p16INK4a and oth ...... ed genes in aging human kidney
@en
Expression of p16INK4a and oth ...... ed genes in aging human kidney
@nl
P2093
P1433
P1476
Expression of p16INK4a and oth ...... ed genes in aging human kidney
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P2093
Anette Melk
Bernhard M W Schmidt
David C Rayner
Oki Takeuchi
P304
P356
10.1111/J.1523-1755.2004.00438.X
P407
P577
2004-02-01T00:00:00Z
P6179
1038226555