Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly
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Type I PIPK-alpha regulates directed cell migration by modulating Rac1 plasma membrane targeting and activationPhosphatidylinositol 4-Phosphate 5-Kinases in the Regulation of T Cell ActivationThe Rac1 hypervariable region in targeting and signaling: a tail of many storiesRho GTPases, phosphoinositides, and actin: a tripartite framework for efficient vesicular traffickingHow cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motilityMembrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signalingSpecific association of nitric oxide synthase-2 with Rac isoforms in activated murine macrophagesIdentification and characterization of a phosphoinositide phosphate kinase homologWAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinasesiRNA Screen Identifies Trafficking Host Factors that Modulate Alphavirus InfectionSingle molecule kinetic analysis of actin filament capping. Polyphosphoinositides do not dissociate capping proteinsThe C-terminal domain of Rac1 contains two motifs that control targeting and signaling specificity.Phosphatidylinositol-4-phosphate 5-kinase and GEP100/Brag2 protein mediate antiangiogenic signaling by semaphorin 3E-plexin-D1 through Arf6 proteinMoesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient.The Ras/Rac guanine nucleotide exchange factor mammalian Son-of-sevenless interacts with PACSIN 1/syndapin I, a regulator of endocytosis and the actin cytoskeleton.The role of heterotrimeric G proteins in platelet activation.Protein kinase C mediates translocation of type II phosphatidylinositol 5-phosphate 4-kinase required for platelet alpha-granule secretion.Sip1, an AP-1 accessory protein in fission yeast, is required for localization of Rho3 GTPase.Activation of Dbl restores migration in polyamine-depleted intestinal epithelial cells via Rho-GTPases.GRK5 promotes F-actin bundling and targets bundles to membrane structures to control neuronal morphogenesisAjuba is required for Rac activation and maintenance of E-cadherin adhesion.Cytoskeletal regulation: rich in lipids.Resolution of structure of PIP5K1A reveals molecular mechanism for its regulation by dimerization and dishevelled.Rac and Cdc42 play distinct roles in regulating PI(3,4,5)P3 and polarity during neutrophil chemotaxis.Arf6 and phosphoinositol-4-phosphate-5-kinase activities permit bypass of the Rac1 requirement for beta1 integrin-mediated bacterial uptakePhosphatidylinositol 4,5-bisphosphate induces actin stress-fiber formation and inhibits membrane ruffling in CV1 cells.A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family.PtdIns-4,5-P2 as a potential therapeutic target for pathologic angiogenesis.Quantitative properties and receptor reserve of the IP(3) and calcium branch of G(q)-coupled receptor signaling.Regulation of PIP5K activity by Arf6 and its physiological significance.Rho GTPases in platelet functionThe multifaceted role of PIP2 in leukocyte biology.Acting on Actin: Rac and Rho Played by Yersinia.Crosstalk of cell polarity signaling pathways.Cell invasion of Yersinia pseudotuberculosis by invasin and YadA requires protein kinase C, phospholipase C-gamma1 and Akt kinase.Phosphatidylinositol 4-phosphate 5-kinase reduces cell surface expression of the epithelial sodium channel (ENaC) in cultured collecting duct cells.Ezrin-related Phosphoinositide pathway modifies RhoA and Rac1 in human osteosarcoma cell lines.Rapid vesicular translocation and insertion of TRP channels.Activation of type I phosphatidylinositol 4-phosphate 5-kinase isoforms by the Rho GTPases, RhoA, Rac1, and Cdc42.Phosphatidylinositol-4-phosphate 5-kinase-1beta is essential for epidermal growth factor receptor-mediated endocytosis.
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Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly
description
article
@en
im Februar 2000 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в лютому 2000
@uk
name
Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly
@en
Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly
@nl
type
label
Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly
@en
Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly
@nl
prefLabel
Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly
@en
Type Iα phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly
@nl
P2093
P1433
P1476
Type Ialpha phosphatidylinosit ...... s Rac-dependent actin assembly
@en
P2093
C L Carpenter
H Ishihara
J H Hartwig
L C Cantley
Y Shibasaki
P304
P356
10.1016/S0960-9822(00)00315-8
P407
P50
P577
2000-02-01T00:00:00Z