Novel antibodies against GPIbα inhibit pulmonary metastasis by affecting vWF-GPIbα interaction

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Novel antibodies against GPIbα inhibit pulmonary metastasis by affecting vWF-GPIbα interaction

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scientific article published on 17 September 2018

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wetenschappelijk artikel

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наукова стаття, опублікована у вересні 2018

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Novel antibodies against GPIbα ...... ffecting vWF-GPIbα interaction

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Novel antibodies against GPIbα ...... ffecting vWF-GPIbα interaction

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Novel antibodies against GPIbα ...... ffecting vWF-GPIbα interaction

@en

Novel antibodies against GPIbα ...... ffecting vWF-GPIbα interaction

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Novel antibodies against GPIbα ...... ffecting vWF-GPIbα interaction

@en

Novel antibodies against GPIbα ...... ffecting vWF-GPIbα interaction

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P1476

Novel antibodies against GPIbα ...... ffecting vWF-GPIbα interaction

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P2093

Fengying Wu

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Jianwen Liu

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Junling Liu

http://www.w3.org/2001/XMLSchema#string

Ke Xu

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Shengxiang Ren

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Wenchun Chen

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Xiangyu Gu

http://www.w3.org/2001/XMLSchema#string

Xinyu Liang

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Xuemei Fan

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Yingxue Qi

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P2860

Platelet glycoprotein IIb/IIIa antagonists: lessons learned from clinical trials and future directions

P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis, and cancer growth and metastasis

Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome

Epitope mapping of inhibitory antibodies against platelet glycoprotein Ibalpha reveals interaction between the leucine-rich repeat N-terminal and C-terminal flanking domains of glycoprotein Ibalpha.

Structural and functional characterization of the mouse von Willebrand factor receptor GPIb-IX with novel monoclonal antibodies.

Antithrombotic effect of platelet glycoprotein Ib-blocking monoclonal antibody Fab fragments in nonhuman primates.

Inhibition of tumor cell-induced platelet aggregation and lung metastasis by the oral GpIIb/IIIa antagonist XV454.

Complement-independent Ab-induced peroxide lysis of platelets requires 12-lipoxygenase and a platelet NADPH oxidase pathway.

The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies.

Role of adhesive proteins in platelet tumor interaction in vitro and metastasis formation in vivo.

P2888

s13045-018-0659-4

P304

117

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scholarly article

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10.1186/S13045-018-0659-4

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English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Renhao Li

Jun Zhang

Xin Liang

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2018-09-17T00:00:00Z

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P6179

1107066787

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P698

30223883

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P921

hematology

cancer research

molecular biology

P932

6142402

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