Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1. - Wikidata - wikimedia - TriplyDB

Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1.

Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1.

http://www.wikidata.org/entity/Q35639741

about

Control of macrophage metabolism and activation by mTOR and Akt signaling Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling Methane limit LPS-induced NF-κB/MAPKs signal in macrophages and suppress immune response in mice by enhancing PI3K/AKT/GSK-3β-mediated IL-10 expression Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock.The Fate of the Tumor in the Hands of Microenvironment: Role of TAMs and mTOR Pathway.FOXO transcription factors: their clinical significance and regulation.Proteomic anaysis of aged microglia: shifts in transcription, bioenergetics, and nutrient response.Dynamic modulation of innate immune response by varying dosages of lipopolysaccharide (LPS) in human monocytic cells.Pathophysiology of cisplatin-induced acute kidney injury.Adenosine triphosphate-competitive mTOR inhibitors: a new class of immunosuppressive agents that inhibit allograft rejection FOXO1, TGF-β regulation and wound healing Innate immune programing by endotoxin and its pathological consequences An mTOR kinase inhibitor slows disease progression in a rat model of polycystic kidney disease Cobalt protoporphyrin induces HO-1 expression mediated partially by FOXO1 and reduces mitochondria-derived reactive oxygen species production FOXO1 mediates RANKL-induced osteoclast formation and activity.FOXO1 deletion reduces dendritic cell function and enhances susceptibility to periodontitis.FOXO1 regulates dendritic cell activity through ICAM-1 and CCR7 mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.Forkhead Box O1 Regulates Macrophage Polarization Following Staphylococcus aureus Infection: Experimental Murine Data and Review of the Literature.Mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons Inhibition of GSK3 abolishes bacterial-induced periodontal bone loss in mice.Negative regulation of TLR signaling in myeloid cells--implications for autoimmune diseases.Effect of Aging on Periodontal Inflammation, Microbial Colonization, and Disease Susceptibility.Murine dendritic cell rapamycin-resistant and rictor-independent mTOR controls IL-10, B7-H1, and regulatory T-cell induction FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype.Chronic Repression of mTOR Complex 2 Induces Changes in the Gut Microbiota of Diet-induced Obese Mice.Rapamycin induces mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) expression through activation of protein kinase B and mitogen-activated protein kinase kinase pathways.Distinct signaling pathways regulate TLR2 co-stimulatory function in human T cells.Adaptive inflammatory microenvironment for cell-based regeneration in ischemic cardiovascular disease.Tunneling nanotube formation is stimulated by hypoxia in ovarian cancer cells.Syk negatively regulates TLR4-mediated IFNβ and IL-10 production and promotes inflammatory responses in dendritic cells.Immune responses of macrophages and dendritic cells regulated by mTOR signalling.Protein kinase networks that limit TLR signalling.The emerging role of mTOR signalling in antibacterial immunity.Evolving perspectives of mTOR complexes in immunity and transplantation.period-Regulated Feeding Behavior and TOR Signaling Modulate Survival of Infection.Regulation of innate immune cell function by mTOR.Roles of mTOR complexes in the kidney: implications for renal disease and transplantation.mTOR-Mediated Regulation of Dendritic Cell Differentiation and Function.

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Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates Toll-like receptor 4-mediated inflammatory response via FoxO1.

http://www.wikidata.org/entity/Q35639741

description

2011 nî lūn-bûn

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2011年論文

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name

Mammalian target of rapamycin ...... flammatory response via FoxO1.

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Mammalian target of rapamycin ...... flammatory response via FoxO1.

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type

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Mammalian target of rapamycin ...... flammatory response via FoxO1.

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Mammalian target of rapamycin ...... flammatory response via FoxO1.

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Mammalian target of rapamycin ...... flammatory response via FoxO1.

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Mammalian target of rapamycin ...... flammatory response via FoxO1.

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JBC.M111.258053

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Journal of Biological Chemistry

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Mammalian target of rapamycin ...... flammatory response via FoxO1.

@en

P2093

Dana T Graves

http://www.w3.org/2001/XMLSchema#string

Huizhi Wang

http://www.w3.org/2001/XMLSchema#string

Jonathan Brown

http://www.w3.org/2001/XMLSchema#string

Michael Martin

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P2860

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action

Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs

The phosphoinositide 3-kinase pathway

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44295-44305

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scholarly article

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52

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286

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Toll-like receptor

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3247956

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