about
Single-nucleotide polymorphisms in the p53 pathway regulate fertility in humansp53 regulates maternal reproduction through LIFThe origins and evolution of the p53 family of genes.Negative regulation of tumor suppressor p53 by microRNA miR-504A plausible model for the digital response of p53 to DNA damage.Detection of functional single-nucleotide polymorphisms that affect apoptosisGene Amplifications in Well-Differentiated Pancreatic Neuroendocrine Tumors Inactivate the p53 Pathway.MDM2 is a central node in the p53 pathway: 12 years and counting.Regulation of female reproduction by p53 and its family membersParkin, a p53 target gene, mediates the role of p53 in glucose metabolism and the Warburg effectChronic restraint stress attenuates p53 function and promotes tumorigenesis.Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations.The Regulation of Multiple p53 Stress Responses is Mediated through MDM2Reconstructing signal transduction pathways: challenges and opportunities.The tumor suppressor p53: cancer and aging.p53: a new player in reproduction.A polymorphic variant in human MDM4 associates with accelerated age of onset of estrogen receptor negative breast cancerTumour-associated mutant p53 drives the Warburg effectDifferential levels of transcription of p53-regulated genes by the arginine/proline polymorphism: p53 with arginine at codon 72 favors apoptosis.The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways.A single nucleotide polymorphism in the MDM2 gene disrupts the oscillation of p53 and MDM2 levels in cells.A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans.Multiple roles of p53-related pathways in somatic cell reprogramming and stem cell differentiation.A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models.The regulation of human reproduction by p53 and its pathway
P50
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P50
description
researcher
@en
wetenschapper
@nl
name
Wenwei Hu
@en
Wenwei Hu
@nl
type
label
Wenwei Hu
@en
Wenwei Hu
@nl
prefLabel
Wenwei Hu
@en
Wenwei Hu
@nl
P31
P496
0000-0003-3971-4257