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Q39385204-C574857E-C7E2-4B28-A943-E59BB7E1AA3B
Q39385204-C574857E-C7E2-4B28-A943-E59BB7E1AA3B
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39385204-C574857E-C7E2-4B28-A943-E59BB7E1AA3B
The deubiquitination enzyme USP46 functions as a tumor suppressor by controlling PHLPP-dependent attenuation of Akt signaling in colon cancer.
P2860
Q39385204-C574857E-C7E2-4B28-A943-E59BB7E1AA3B
BestRank
Statement
http://www.wikidata.org/entity/statement/Q39385204-C574857E-C7E2-4B28-A943-E59BB7E1AA3B
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wasDerivedFrom
668a22312486d712ddff07fcd00da56c754efee0
P2860
Mislocalization of the E3 ligase, β-transducin repeat-containing protein 1 (β-TrCP1), in glioblastoma uncouples negative feedback between the pleckstrin homology domain leucine-rich repeat protein phosphatase 1 (PHLPP1) and Akt.